Pharmacological interventions in human aging
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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Pharmacological interventions in human aging. / Petr, Michael Angelo; Matiyevskaya, Frida; Osborne, Brenna; Berglind, Magnus; Reves, Simon; Zhang, Bin; Ezra, Michael Ben; Carmona-Marin, Lina Maria; Syadzha, Muhammad Farraz; Mediavilla, Marta Cortés; Keijzers, Guido; Bakula, Daniela; Mkrtchyan, Garik V.; Scheibye-Knudsen, Morten.
I: Ageing Research Reviews, Bind 95, 102213, 2024.Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
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TY - JOUR
T1 - Pharmacological interventions in human aging
AU - Petr, Michael Angelo
AU - Matiyevskaya, Frida
AU - Osborne, Brenna
AU - Berglind, Magnus
AU - Reves, Simon
AU - Zhang, Bin
AU - Ezra, Michael Ben
AU - Carmona-Marin, Lina Maria
AU - Syadzha, Muhammad Farraz
AU - Mediavilla, Marta Cortés
AU - Keijzers, Guido
AU - Bakula, Daniela
AU - Mkrtchyan, Garik V.
AU - Scheibye-Knudsen, Morten
N1 - Publisher Copyright: © 2024
PY - 2024
Y1 - 2024
N2 - Pharmacological interventions are emerging as potential avenues of alleviating age-related disease. However, the knowledge of ongoing clinical trials as they relate to aging and pharmacological interventions is dispersed across a variety of mediums. In this review we summarize 136 age-related clinical trials that have been completed or are ongoing. Furthermore, we establish a database that describe the trials (AgingDB, www.agingdb.com) keeping track of the previous and ongoing clinical trials, alongside their outcomes. The aim of this review and database is to give people the ability to easily query for their trial of interest and stay up to date on the latest results. In sum, herein we give an overview of the current pharmacological strategies that have been applied to target human aging.
AB - Pharmacological interventions are emerging as potential avenues of alleviating age-related disease. However, the knowledge of ongoing clinical trials as they relate to aging and pharmacological interventions is dispersed across a variety of mediums. In this review we summarize 136 age-related clinical trials that have been completed or are ongoing. Furthermore, we establish a database that describe the trials (AgingDB, www.agingdb.com) keeping track of the previous and ongoing clinical trials, alongside their outcomes. The aim of this review and database is to give people the ability to easily query for their trial of interest and stay up to date on the latest results. In sum, herein we give an overview of the current pharmacological strategies that have been applied to target human aging.
KW - Age-associated diseases
KW - Aging
KW - Clinical trials
KW - Database
KW - Pharmacological interventions
KW - Small molecules
U2 - 10.1016/j.arr.2024.102213
DO - 10.1016/j.arr.2024.102213
M3 - Review
C2 - 38309591
AN - SCOPUS:85185590279
VL - 95
JO - Ageing Research Reviews
JF - Ageing Research Reviews
SN - 1568-1637
M1 - 102213
ER -
ID: 384256335