Impact of lifestyle and clinical interventions on mitochondrial function in obesity and type 2 diabetes
Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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Impact of lifestyle and clinical interventions on mitochondrial function in obesity and type 2 diabetes. / Osborne, Brenna; Brandon, Amanda E.; Smith, Greg C.; Turner, Nigel.
Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases. Academic Press, 2019. s. 367-397.Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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TY - CHAP
T1 - Impact of lifestyle and clinical interventions on mitochondrial function in obesity and type 2 diabetes
AU - Osborne, Brenna
AU - Brandon, Amanda E.
AU - Smith, Greg C.
AU - Turner, Nigel
PY - 2019
Y1 - 2019
N2 - Lifestyle interventions are the first line of defense employed by many clinicians to both treat and prevent metabolic disorders associated with obesity, such as type 2 diabetes. Other clinical interventions, such as surgery, also are being rapidly implemented for these groups of patients. There is growing evidence that the benefit of these lifestyle and surgical treatments for patients might be driven by effects on mitochondrial function. This chapter will discuss the current knowledge about the influence of lifestyle and clinical interventions on mitochondrial health. The effects of lifestyle interventions such as dietary intervention, exercise, and physical training regimes, cessation of smoking, and cessation of alcohol will be discussed. Highly effective nonpharmacological clinical interventions, such as bariatric surgery and its effects on mitochondrial health, will also be reviewed.
AB - Lifestyle interventions are the first line of defense employed by many clinicians to both treat and prevent metabolic disorders associated with obesity, such as type 2 diabetes. Other clinical interventions, such as surgery, also are being rapidly implemented for these groups of patients. There is growing evidence that the benefit of these lifestyle and surgical treatments for patients might be driven by effects on mitochondrial function. This chapter will discuss the current knowledge about the influence of lifestyle and clinical interventions on mitochondrial health. The effects of lifestyle interventions such as dietary intervention, exercise, and physical training regimes, cessation of smoking, and cessation of alcohol will be discussed. Highly effective nonpharmacological clinical interventions, such as bariatric surgery and its effects on mitochondrial health, will also be reviewed.
KW - Alcohol
KW - Bariatric surgery
KW - Calorie restriction
KW - Exercise
KW - Mitochondria
KW - Smoking
KW - Type 2 diabetes
U2 - 10.1016/B978-0-12-811752-1.00016-X
DO - 10.1016/B978-0-12-811752-1.00016-X
M3 - Book chapter
AN - SCOPUS:85083227104
SN - 9780128118597
SP - 367
EP - 397
BT - Mitochondria in Obesity and Type 2 Diabetes
PB - Academic Press
ER -
ID: 241096327