GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients
Research output: Contribution to journal › Journal article › Research › peer-review
Disproportionate growth of musculoskeletal tissue is a major cause of morbidity in both acromegalic (ACRO) and GH-deficient (GHD) patients. GH/IGF1 is likely to play an important role in the regulation of tendon and muscle collagen. We hypothesized that the local production of collagen is associated with the level of GH/IGF1.
| Original language | English |
|---|---|
| Journal | European Journal of Endocrinology |
| Volume | 163 |
| Issue number | 6 |
| Pages (from-to) | 853-62 |
| Number of pages | 10 |
| ISSN | 0804-4643 |
| DOIs | |
| Publication status | Published - Dec 2010 |
- Adult, Collagen, Collagen Type I, Collagen Type III, Human Growth Hormone, Humans, Insulin-Like Growth Factor Binding Protein 3, Insulin-Like Growth Factor I, Male, Microscopy, Electron, Transmission, Middle Aged, Muscle, Skeletal, RNA, Messenger, Tendons
Research areas
ID: 32321075