Forty-Five-Year Mortality Rate as a Function of the Number and Type of Psychiatric Diagnoses Found in a Large Danish Birth Cohort
Research output: Contribution to journal › Journal article › Research › peer-review
Objective: Psychiatric comorbidities are common among psychiatric patients and typically associated with poorer clinical prognoses. Subjects of a large Danish birth cohort were used to study the relation between mortality and co-occurring psychiatric diagnoses. Method: We searched the Danish Central Psychiatric Research Registry for 8109 birth cohort members aged 45 years. Lifetime psychiatric diagnoses (International Classification of Diseases, Revision 10, group F codes, Mental and Behavioural Disorders, and one Z code) for identified subjects were organized into 14 mutually exclusive diagnostic categories. Mortality rates were examined as a function of number and type of co-occurring diagnoses. Results: Psychiatric outcomes for 1247 subjects were associated with 157 deaths. Early mortality risk in psychiatric patients correlated with the number of diagnostic categories (Wald ¿² = 25.0, df = 1, P <0.001). This global relation was true for anxiety and personality disorders, but not for schizophrenia and substance abuse, which had intrinsically high mortality rates with no comorbidities. Conclusions: Risk of early mortality among psychiatric patients appears to be a function of both the number and the type of psychiatric diagnoses.
Original language | English |
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Journal | Canadian Journal of Psychiatry |
Volume | 57 |
Issue number | 8 |
Pages (from-to) | 505-511 |
Number of pages | 7 |
ISSN | 0706-7437 |
Publication status | Published - 2012 |
ID: 40995120