TY - JOUR

T1 - Mortality of older acutely admitted medical patients after early discharge from emergency departments

T2 - a nationwide cohort study [Incl. correction]

AU - Aasbrenn, Martin

AU - Christiansen, Christian Fynbo

AU - Esen, Buket Öztürk

AU - Suetta, Charlotte

AU - Nielsen, Finn Erland

N1 - Correction: DOI: https://doi.org/10.1186/s12877-021-02420-6

PY - 2021

Y1 - 2021

N2 - Background: The mortality of older patients after early discharge from hospitals is sparsely described. Informationon factors associated with mortality can help identify high-risk patients who may benefit from preventiveinterventions. The aim of this study was to examine whether demographic factors, comorbidity and admissiondiagnoses are predictors of 30-day mortality among acutely admitted older patients discharged within 24 h afteradmission.Methods: All medical patients aged ≥65 years admitted acutely to Danish hospitals between 1 January 2013 and30 June 2014 surviving a hospital stay of ≤24 h were included. Demographic factors, comorbidity, dischargediagnoses and mortality within 30 days were described using data from the Danish National Patient Registry andthe Civil Registration System. Cox regression was used to estimate adjusted hazard ratios (aHR) with 95%confidence intervals (CI) for all-cause mortality.Results: A total of 93,295 patients (49.4% men) with a median age of 75 years (interquartile range: 69–82 years),were included. Out of these, 2775 patients (3.0%; 95% CI 2.9–3.1%) died within 30 days after discharge. The 30-daymortality was increased in patients with age 76–85 years (aHR 1.59; 1.45–1.75) and 86+ years (aHR 3.35; 3.04–3.70),male gender (aHR 1.22; 1.11–1.33), a Charlson Comorbidity Index of 1–2 (aHR 2.15; 1.92–2.40) and 3+ (aHR 4.07;3.65–4.54), and unmarried status (aHR 1.17; 1.08–1.27). Discharge diagnoses associated with 30-day mortality wereheart failure (aHR 1.52; 1.17–1.95), respiratory failure (aHR 3.18; 2.46–4.11), dehydration (aHR 2.87; 2.51–3.29),constipation (aHR 1.31; 1.02–1.67), anemia (aHR 1.45; 1.27–1.66), pneumonia (aHR 2.24; 1.94–2.59), urinary tractinfection (aHR 1.33; 1.14–1.55), dyspnea (aHR 1.57; 1.32–1.87) and suspicion of malignancy (aHR 2.06; 1.64–2.59).

AB - Background: The mortality of older patients after early discharge from hospitals is sparsely described. Informationon factors associated with mortality can help identify high-risk patients who may benefit from preventiveinterventions. The aim of this study was to examine whether demographic factors, comorbidity and admissiondiagnoses are predictors of 30-day mortality among acutely admitted older patients discharged within 24 h afteradmission.Methods: All medical patients aged ≥65 years admitted acutely to Danish hospitals between 1 January 2013 and30 June 2014 surviving a hospital stay of ≤24 h were included. Demographic factors, comorbidity, dischargediagnoses and mortality within 30 days were described using data from the Danish National Patient Registry andthe Civil Registration System. Cox regression was used to estimate adjusted hazard ratios (aHR) with 95%confidence intervals (CI) for all-cause mortality.Results: A total of 93,295 patients (49.4% men) with a median age of 75 years (interquartile range: 69–82 years),were included. Out of these, 2775 patients (3.0%; 95% CI 2.9–3.1%) died within 30 days after discharge. The 30-daymortality was increased in patients with age 76–85 years (aHR 1.59; 1.45–1.75) and 86+ years (aHR 3.35; 3.04–3.70),male gender (aHR 1.22; 1.11–1.33), a Charlson Comorbidity Index of 1–2 (aHR 2.15; 1.92–2.40) and 3+ (aHR 4.07;3.65–4.54), and unmarried status (aHR 1.17; 1.08–1.27). Discharge diagnoses associated with 30-day mortality wereheart failure (aHR 1.52; 1.17–1.95), respiratory failure (aHR 3.18; 2.46–4.11), dehydration (aHR 2.87; 2.51–3.29),constipation (aHR 1.31; 1.02–1.67), anemia (aHR 1.45; 1.27–1.66), pneumonia (aHR 2.24; 1.94–2.59), urinary tractinfection (aHR 1.33; 1.14–1.55), dyspnea (aHR 1.57; 1.32–1.87) and suspicion of malignancy (aHR 2.06; 1.64–2.59).

UR - https://doi.org/10.1186/s12877-021-02420-6

U2 - 10.1186/s12877-021-02355-y

DO - 10.1186/s12877-021-02355-y

M3 - Journal article

C2 - 34215192

VL - 21

JO - B M C Geriatrics

JF - B M C Geriatrics

SN - 1471-2318

M1 - 410

ER -