Center for Healthy Aging

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  1. 2020
  2. Published

    Mitochondrial dysfunction induced by variation in the non-coding genome – A proposed workflow to improve diagnostics

    du Mee, D. J. M., Bak, M., Østergaard, Elsebet & Rasmussen, Lene Juel, 2020, In: Mitochondrion. 53, p. 255-259

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    MitophAging: Mitophagy in Aging and Disease

    Bakula, Daniela Janina & Scheibye-Knudsen, Morten, 2020, In: Frontiers in Cell and Developmental Biology. 8, 16 p., 239.

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Mitophagy and Neuroprotection

    Lou, G., Palikaras, K., Lautrup, S., Scheibye-Knudsen, Morten, Tavernarakis, N. & Fang, E. F., 2020, In: Trends in Molecular Medicine. 26, 1, p. 8-20

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    Modification of oxygen consumption and blood flow in mouse somatosensory cortex by cell-type-specific neuronal activity

    Dahlqvist, M. K., Thomsen, Kirsten Joan, Postnov, D. D. & Lauritzen, Martin, 2020, In: Journal of Cerebral Blood Flow and Metabolism. 40, 10, p. 2010-2025 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Mortality Following Trajectories of Mobility Limitations: The Modifying Impact of Social Factors

    Jørgensen, Terese Sara Høj, Siersma, Volkert Dirk, Lund, Rikke & Nilsson, Charlotte Juul, 2020, In: Journal of Aging and Health. 32, 3-4, p. 134-142 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    New methodologies in ageing research

    Osborne, Brenna, Bakula, Daniela Janina, Ben Ezra, Michael, Dresen, C., Hartmann, E., Kristensen, S. M., Mkrtchyan, Garik, Nielsen, M. H., Petr, Michael Angelo & Scheibye-Knudsen, Morten, 2020, In: Ageing Research Reviews. 62, 11 p., 101094.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    No detectable remodelling in adult human menisci: an analysis based on the C14 bomb pulse

    Våben, C., Heinemeier, K. M., Schjerling, P., Olsen, J., Petersen, Michael Mørk, Kjær, Michael & Krogsgaard, Michael R., 2020, In: British Journal of Sports Medicine. 54, 23, p. 1433-1437

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Onset of Workplace Bullying and Risk of Weight Gain: A Multicohort Longitudinal Study

    Xu, Tianwei, Magnusson Hanson, L. L., Clark, A. J., Ersbøll, A. K., Westerlund, H., Madsen, I. E. H., Rugulies, Reiner Ernst, Pentti, J., Stenholm, S., Vahtera, J., Sørensen, J. K., Nordentoft, M., Westendorp, Rudi GJ, Hansen, Åse Marie, Oksanen, T., Virtanen, M., Kivimäki, M. & Rod, Naja Hulvej, 2020, In: Obesity. 28, 11, p. 2216-2223 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Perceived stress and dementia: Results from the Copenhagen city heart study

    Nabe-Nielsen, Kirsten, Rod, Naja Hulvej, Hansen, Åse Marie, Prescott, Eva, Grynderup, M. B., Islamoska, S., Ishtiak-Ahmed, K., Garde, Anne Helene, Gyntelberg, F., Mortensen, Erik Lykke, Thien Kieu Thi Phung, Waldemar, Gunhild & Westendorp, Rudi GJ, 2020, In: Aging & Mental Health. 24, 11, p. 1828-1836 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans

    Morville, T., Sahl, Ronni Eg, Moritz, Thomas, Helge, Jørn Wulff & Clemmensen, Christoffer, 2020, In: Cell Reports. 33, 13, 14 p., 108554.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Possible Modifiers of the Association Between Change in Weight Status From Child Through Adult Ages and Later Risk of Type 2 Diabetes

    Bjerregaard, L. G., Wasenius, N., Nedelec, R., Gjærde, L. K., Ängquist, Lars, Herzig, K., Jensen, G. B., Mortensen, Erik Lykke, Osler, Merete, Overvad, K., Skaaby, T., Tjønneland, Anne, Sørensen, Thorkild I.A., Järvelin, M., Eriksson, J. G., Sebert, S. & Baker, J. L., 2020, In: Diabetes Care. Supplement. 43, 5, p. 1000-1007 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Preserved capacity for satellite cell proliferation, regeneration, and hypertrophy in the skeletal muscle of healthy elderly men

    Karlsen, Anders, Soendenbroe, C., Malmgaard‐clausen, N. M., Wagener, F., Moeller, C. E., Senhaji, Z., Damberg, K., Andersen, J. L., Schjerling, P., Kjær, Michael & Mackey, Abigail, 2020, In: The FASEB Journal. 34, 5, p. 6418-6436

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Protecting the Aging Genome

    Petr, Michael Angelo, Tulika, T., Carmona Marin, Lina Maria & Scheibye-Knudsen, Morten, 2020, In: Trends in Cell Biology. 30, 2, p. 117-132 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Proteomics identifies differences in fibrotic potential of extracellular vesicles from human tendon and muscle fibroblasts

    Yeung, C. C., Schoof, E. M., Tamáš, M., Mackey, Abigail & Kjær, Michael, 2020, In: Cell Communication and Signaling. 18, 1, 15 p., 177.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome

    Wu, Wei, Bhowmick, Rahul, Vogel, Ivan, Özer, Ö., Ghisays, F., Thakur, R. S., Sanchez de Leon, E., Richter, P. H., Ren, L., Petrini, J. H., Hickson, Ian David & Liu, Ying, 2020, In: Nature Structural & Molecular Biology. 27, 5, p. 424-437 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Regional collagen turnover and composition of the human patellar tendon

    Zhang, C., Couppé, Christian, Scheijen, J. L. J. M., Schalkwijk, C. G., Kjær, Michael, Magnusson, Stig Peter & Svensson, R. B., 2020, In: Journal of Applied Physiology. 128, 4, p. 884-891

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Regional differences in turnover, composition, and mechanics of the porcine flexor tendon

    Zhang, C., Svensson, R. B., Couppé, Christian, Schjerling, P., Skovgaard, D., Kjær, Michael & Magnusson, Stig Peter, 2020, In: Connective Tissue Research. 61, 5, p. 475-484

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes

    Xing, M., Zhang, F., Liao, H., Chen, S., Che, L., Wang, X., Bao, Z., Ji, F., Chen, G., Zhang, H., Li, W., Chen, Z., Liu, Ying, Hickson, Ian David, Shen, H. & Ying, S., 2020, In: Molecular Cell. 78, 4, p. 714-724.e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Reply to Dutheil et al

    Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Journal of applied physiology (Bethesda, Md. : 1985). 129, 1, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  21. Published

    Self-Disorders in Asperger Syndrome Compared to Schizotypal Disorder: A Clinical Study

    Nilsson, M., Arnfred, Sidse Marie , Lohmann, Jessica Mariana Carlsson, Nylander, L., Pedersen, L., Mortensen, Erik Lykke & Handest, P., 2020, In: Schizophrenia Bulletin. 46, 1, p. 121-129

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

    Covarrubias, A. J., Kale, A., Perrone, R., Lopez-Dominguez, J. A., Pisco, A. O., Kasler, H. G., Schmidt, M. S., Heckenbach, I., Kwok, R., Wiley, C. D., Wong, H. S., Gibbs, E., Iyer, S. S., Basisty, N., Wu, Q., Kim, I. J., Silva, E., Vitangcol, K., Shin, K. O., Lee, Y. M. & 11 others, Riley, R., Ben-Sahra, I., Ott, M., Schilling, B., Scheibye-Knudsen, Morten, Ishihara, K., Quake, S. R., Newman, J., Brenner, C., Campisi, J. & Verdin, E., 2020, In: Nature Metabolism. 2, 11, p. 1265-1283 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Serotonin transporter gene (SLC6A4) variation and sensory processing sensitivity—Comparison with other anxiety-related temperamental dimensions

    Licht, C. L., Mortensen, Erik Lykke, Hjordt, L. V., Stenbæk, Dea Siggaard, Arentzen, T. E., Nørremølle, Anne & Knudsen, Gitte Moos, 2020, In: Molecular Genetics and Genomic Medicine. 8, 8, 10 p., e1352.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Shift work and incidence of dementia: A Danish Nurse Cohort study

    Jørgensen, J. T., Hansen, J., Westendorp, Rudi GJ, Nabe-Nielsen, Kirsten, Stayner, L. T., Simonsen, M. K. & Andersen, Zorana Jovanovic, 2020, In: Alzheimer's and Dementia. 16, 9, p. 1268-1279 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Simvastatin improves mitochondrial respiration in peripheral blood cells

    Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Skeletal Effects of Levothyroxine for Subclinical Hypothyroidism in Older Adults: A TRUST Randomized Trial Nested Study

    Gonzalez Rodriguez, E., Stuber, M., Del Giovane, C., Feller, M., Collet, T. H., Löwe, A. L., Blum, M. R., van Vliet, N. A., van Heemst, D., Kearney, P. M., Gussekloo, J., Mooijaart, S., Westendorp, Rudi GJ, Stott, D. J., Aeberli, D., Bauer, D. C., Hans, D. & Rodondi, N., 2020, In: The Journal of clinical endocrinology and metabolism. 105, 1, p. 336–343 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Skærmbesøg: det sundhedsfaglige blik i en Coronatid

    Grünenberg, Kristina, Hillersdal, Line & Winther, J., 2020, In: Tidsskrift for forskning i sygdom og samfund. 17, 33, p. 189-195

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Social Relations, Community Engagement and Potentials: A Qualitative Study Exploring Resident Engagement in a Community-Based Health Promotion Intervention in a Deprived Social Housing Area

    Srivarathan, Abirami, Lund, Rikke, Christensen, Ulla & Kristiansen, Maria, 2020, In: International Journal of Environmental Research and Public Health. 17, 7, 18 p., 2341.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease

    Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Desler, Claus, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In: iScience. 23, 10, 42 p., 101556.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Steady-state visual evoked potential temporal dynamics reveal correlates of cognitive decline

    Richard, N., Nikolic, M., Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin & Benedek, K., 2020, In: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 131, 4, p. 836-846 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Supraphysiological protection from replication stress does not extend mammalian lifespan

    Albers, E., Avram, Alexandra Ioana, Sbroggio, M., Fernandez-Capetillo, O. & Lopez-Contreras, Andres, 2020, In: Aging. 12, 7, p. 5612-5624 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    TIP60 in aging and neurodegeneration

    Li, Zhiquan & Rasmussen, Lene Juel, 2020, In: Ageing Research Reviews. 64, 101195.

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing

    Gilmour, B. C., Gudmundsrud, R., Frank, J., Hov, A., Lautrup, S., Aman, Y., Rosjo, H., Brenner, C., Ziegler, M., Tysnes, O., Tzoulis, C., Omland, T., Soraas, A., Holmoy, T., Bergersen, L. H., Storm-Mathisen, J., Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 186, 6 p., 111208.

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    The Children's Yale-Brown Obsessive-Compulsive Scale's auxiliary items: Long-term outcome

    Jensen, S., Hybel, K. A., Højgaard, D. R. M. A., Nissen, J. B., Skarphedinsson, G., Torp, N. C., Ivarsson, T., Weidle, B., Mortensen, Erik Lykke, Carlsen, A. H., Melin, K., Compton, S. & Thomsen, P. H., 2020, In: Journal of Obsessive-Compulsive and Related Disorders. 27, 100589.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The Demand-Control model and work-related threats and violence: Short- and long-term associations

    Andersen, L. P., Biering, K., Høgh, A., Gadegaard, C. A. & Conway, Paul Maurice, 2020, In: Work. 65, 3, p. 573-580 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The Modifying Influence of Family Social Background on the Association between IQ and Unsuccessful Educational and Occupational Achievement: A Register-Based Study of 277,938 Men in Denmark 1981-2016

    Hegelund, Emilie Rune, Flensborg-Madsen, Trine, Dammeyer, Jesper & Mortensen, Erik Lykke, 2020, In: Journal of Individual Differences. 41, 3, p. 133-143 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications

    Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells

    Brannvoll, A., Xue, X., Kwon, Y., Kompocholi, Smaragda, Simonsen, Anne Katrine Wrist, Bagge, Keerthana Stine Viswalingam, Gonzalez, L., Hickson, Ian David, Østergaard, Vibe Hallundbæk, Mankouri, H. W., Sung, P. & Lisby, Michael, 2020, In: Cell Reports. 32, 1, 25 p., 107849.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The effect of 4 months exercise training on systemic biomarkers of cartilage and bone turnover in hip osteoarthritis patients

    Ellegaard, M., Bieler, T., Beyer, N., Kjær, Michael & Jørgensen, Niklas Rye, 2020, In: Translational Sports Medicine. 3, 1, p. 16-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The influence of educational attainment on intelligence

    Hegelund, Emilie Rune, Grønkjær, M. S., Osler, Merete, Dammeyer, Jesper, Flensborg-Madsen, Trine & Mortensen, Erik Lykke, 2020, In: Intelligence. 78, 101419.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    The influence of prolonged strength training upon muscle and fat in healthy and chronically diseased older adults

    Gylling, A. T., Eriksen, C. S., Garde, Ellen, Wimmelmann, Cathrine Lawaetz, Reislev, N. L., Bieler, T., Ziegler, A. K., Andersen, K. W., Bauer, C., Dideriksen, K., Bækgaard, M., Mertz, K. H., Bayer, M. L., Bloch-Ibenfeldt, M., Boraxbekk, CJ, Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, 2020, In: Experimental Gerontology. 136, 110939.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The lactate receptor HCA1 is present in the choroid plexus, the tela choroidea, and the neuroepithelial lining of the dorsal part of the third ventricle

    Hadzic, A., Nguyen, T. D., Hosoyamada, M., Tomioka, N. H., Bergersen, L. H., Storm-Mathisen, J. & Morland, C., 2020, In: International Journal of Molecular Sciences. 21, 18, 14 p., 6457.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The many lives of type IA topoisomerases

    Bizard, A. H. & Hickson, Ian David, 2020, In: Journal of Biological Chemistry. 295, 20, p. 7138-7153 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  44. Published

    The prevention and resolution of DNA replication–transcription conflicts in eukaryotic cells

    Wu, Wei, Hickson, Ian David & Liu, Ying, 2020, In: Genome Instability & Disease. 1, 3, p. 114–128 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    The relationship between peak fat oxidation and prolonged double-poling endurance exercise performance

    Rømer, Tue, Hansen, Mikkel Thunestvedt, Frandsen, J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Scandinavian Journal of Medicine & Science in Sports. 30, 11, p. 2044-2056

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure

    Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Towards Inclusive Healthcare Delivery: Potentials and Challenges of Human-Centred Design in Health Innovation Processes to Increase Healthy Aging

    Sandholdt, Catharina Thiel, Cunningham, J., Westendorp, Rudi GJ & Kristiansen, Maria, 2020, In: International Journal of Environmental Research and Public Health. 17, 12, 9 p., 4551.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Trauma-affected refugees treated with basic body awareness therapy or mixed physical activity as augmentation to treatment as usual -A pragmatic randomised controlled trial

    Nordbrandt, M. S., Sonne, C., Mortensen, Erik Lykke & Carlsson, J., 2020, In: PLoS ONE. 15, 3, 16 p., e0230300.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Traumatic brain injury and risk of dementia at different levels of cognitive ability and education

    Osler, Merete, Rozing, Maarten Pieter, Eliasen, M. H., Christensen, K. & Mortensen, Erik Lykke, 2020, In: European Journal of Neurology. 27, 2, p. 399-405 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Treatment with imagery rehearsal therapy and/or mianserin in trauma-affected refugees: results from a randomized controlled trial

    Sandahl, H., Jennum, Poul, Baandrup, Lone, Mortensen, Erik Lykke & Carlsson, J., 2020, In: Journal of Sleep Research. 29, S1, p. 22-23 2 p., O41.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  51. Published

    Tumour predisposition and cancer syndromes as models to study gene–environment interactions

    Carbone, M., Arron, S. T., Beutler, B., Bononi, A., Cavenee, W., Cleaver, J. E., Croce, C. M., D’Andrea, A., Foulkes, W. D., Gaudino, G., Groden, J. L., Henske, E. P., Hickson, I. D., Hwang, P. M., Kolodner, R. D., Mak, T. W., Malkin, D., Monnat, R. J., Novelli, F., Pass, H. I. & 3 others, Petrini, J. H., Schmidt, L. S. & Yang, H., 2020, In: Nature Reviews Cancer. 20, p. 533–549

    Research output: Contribution to journal › Journal article › Research › peer-review

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