Center for Healthy Aging

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  1. 2020
  2. Published

    Cardioprotective effect of succinate dehydrogenase inhibition in rat hearts and human myocardium with and without diabetes mellitus

    Jespersen, N. R., Hjortbak, M. V., Lassen, T. R., Støttrup, N. B., Johnsen, J., Tonnesen, P. T., Larsen, Steen, Kimose, H. H. & Bøtker, H. E., 2020, In: Scientific Reports. 10, 1, 15 p., 10344.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Cardiovascular and metabolic health effects of team handball training in overweight women: Impact of prior experience

    Hornstrup, T., Póvoas, S., Helge, Jørn Wulff, Melcher, Pia Grethe Sandfeld, Fristrup, B., Andersen, J. L., Møgelvang, R., Hansen, Peter Riis, Nybo, Lars & Krustrup, P., 2020, In: Scandinavian Journal of Medicine & Science in Sports. 30, 2, p. 281-294 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Cellular senescence and chronological age in various human tissues: A systematic review and meta-analysis

    Tuttle, C. S. L., Waaijer, M. E. C., Slee-Valentijn, M. S., Stijnen, T., Westendorp, Rudi GJ & Maier, A. B., 2020, In: Aging Cell. 19, 2, 11 p., e13083.

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    Circulating Thyroid Hormone Profile in Response to a Triiodothyronine Challenge in Familial Longevity

    Zutinic, A., Blauw, G. J., Pijl, H., Ballieux, B. E., Westendorp, Rudi GJ, Roelfsema, F. & van Heemst, D., 2020, In: Endocrine Research. 4, 10, 9 p., bvaa117.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Cognitive Ability in Midlife and Labor Market Participation Among Older Workers: Prospective Cohort Study With Register Follow-up

    Sundstrup, E., Hansen, Åse Marie, Mortensen, Erik Lykke, Poulsen, O. M., Clausen, T., Rugulies, Reiner Ernst, Møller, Anne & Andersen, L. L., 2020, In: Safety and Health at Work. 11, p. 291-300 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Comparison of Tenocyte Populations from the Core and Periphery of Equine Tendons

    Zhang, C., Svensson, R. B., Montagna, C., Carstensen, Helena, Buhl, Rikke, Schoof, E. M., Kjær, Michael, Magnusson, Stig Peter & Yeung, C. Y. C., 2020, In: Journal of Proteome Research. 19, 10, p. 4137-4144 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Crowdsourcing Hypothesis Tests: Making transparent how design choices shape research results

    Crowdsourced Hypothesis Tests Collaboration, C. H. T. C., 2020, In: Psychological Bulletin. 146, 5, p. 451-479 29 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells

    Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, R. I., Aldana, Blanca, Desler, Claus, Rasmussen, Lene Juel, Sustarsic, E. G., Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In: Frontiers in Immunology. 11, 22 p., 1968.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    DNA damage invokes mitophagy through a pathway involving Spata18

    Dan, X., Babbar, M., Moore, A., Wechter, N., Tian, J., Mohanty, J. G., Croteau, D. L. & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6611-6623 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Discovering correlates of age-related decline in a healthy late-midlife male birth cohort

    Zarnani, K., Smith, S. M., Alfaro-Almagro, F., Fagerlund, Birgitte, Lauritzen, Martin, Rostrup, E. & Nichols, T. E., 2020, In: Aging. 12, 17, p. 16709—16743 35 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Distinct trajectories of long-term symptom severity in pediatric obsessive-compulsive disorder during and after stepped-care treatment

    Jensen, S., Højgaard, D. R. M. A., Hybel, K. A., Mortensen, Erik Lykke, Skarphedinsson, G., Melin, K., Ivarsson, T., Nissen, J. B., Weidle, B., Valderhaug, R., Torp, N. C., Dahl, K., Compton, S. & Thomsen, P. H., 2020, In: Journal of Child Psychology and Psychiatry. 61, 9, p. 969-978 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Do we know the effects of colorectal cancer screening? A short communication on selective uptake and differential effects of colorectal cancer screening in Scandinavia

    Pallesen, Anna Vera Jørring, Herrstedt, Jørn, Westendorp, Rudi GJ, Mortensen, Laust Hvas & Kristiansen, Maria, 2020, In: Scandinavian Journal of Public Health. 49, 8, p. 841-844 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Does Midlife Forgetfulness Influence Positive and Negative Aspects of Social Relations at Work? Results from the Danish Working Environment Cohort Study

    Ishtiak-Ahmed, K., Hansen, Åse Marie, Mortensen, Erik Lykke, Garde, Anne Helene, Grynderup, M. B., Gyntelberg, F., Islamoska, S., Lund, Rikke, Phung, T. K. T., Waldemar, Gunhild & Nabe-Nielsen, Kirsten, 2020, In: Journal of Occupational and Environmental Medicine. 62, 9, p. 738-745 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

    Fontana, D., Mauri, M., Renso, R., Docci, M., Crespiatico, I., Røst, L. M., Jang, M., Niro, A., D’aliberti, D., Massimino, L., Bertagna, M., Zambrotta, G., Bossi, M., Citterio, S., Crescenzi, B., Fanelli, F., Cassina, V., Corti, R., Salerno, D., Nardo, L. & 10 others, Chinello, C., Mantegazza, F., Mecucci, C., Magni, F., Cavaletti, G., Bruheim, P., Rea, D., Larsen, Steen, Gambacorti-passerini, C. & Piazza, R., 2020, In: Nature Communications. 11, 1, 16 p., 5938.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Early Growth Response Genes Increases Rapidly After Mechanical Overloading and Unloading in Tendon Constructs

    Herchenhan, A., Dietrich-Zagonel, F., Schjerling, P., Kjær, Michael & Eliasson, P., 2020, In: Journal of Orthopaedic Research. 38, 1, p. 173-181

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Early development of tendinopathy in humans: Sequence of pathological changes in structure and tissue turnover signaling

    Tran, P. H. T., Malmgaard-Clausen, N. M., Puggaard, R. S., Svensson, R. B., Nybing, J. D., Hansen, P., Schjerling, P., Zinglersen, A. H., Couppé, Christian, Boesen, Mikael Ploug, Magnusson, Stig Peter & Kjær, Michael, 2020, In: FASEB Journal. 34, 1, p. 776-788 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Early life predictors of intelligence in young adulthood and middle age

    Flensborg-Madsen, Trine, Eriksen, H. F. & Mortensen, Erik Lykke, 2020, In: PLoS ONE. 15, 1, 15 p., e0228144.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Economic hardship over twenty-two consecutive years of adult life and markers of early ageing: physical capability, cognitive function and inflammation

    Foverskov, Else, Petersen, G. L., Pedersen, J. L. M., Rod, Naja Hulvej, Mortensen, Erik Lykke, Bruunsgaard, H. & Lund, Rikke, 2020, In: European Journal of Ageing. 17, p. 55-67 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Effect of Platelet-Rich Plasma on Nonsurgically Treated Acute Achilles Tendon Ruptures: A Randomized, Double-Blinded Prospective Study

    Boesen, A. P., Boesen, M. I., Hansen, R., Barfod, Kristoffer Weisskirchner, Lenskjold, A., Malliaras, P. & Langberg, Henning, 2020, In: American Journal of Sports Medicine. 48, 9, p. 2268-2276 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Effect of Thyroid Hormone Therapy on Fatigability in Older Adults with Subclinical Hypothyroidism: A Nested Study within a Randomized Placebo-Controlled Trial

    Stuber, M. J., Moutzouri, E., Feller, M., Del Giovane, C., Bauer, D. C., Blum, M. R., Collet, T. H., Gussekloo, J., Mooijaart, S. P., McCarthy, V. J. C., Aujesky, D., Westendorp, Rudi GJ, Stott, D. J., Glynn, N. W., Kearney, P. M., Rodondi, N. & Newman, A., 2020, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 75, 9, p. e89-e94 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Effects of small-sided recreational team handball training on mechanical muscle function, body composition and bone mineralization in untrained young adults - A randomized controlled trial

    Fristrup, B., Krustrup, P., Andersen, J. L., Hornstrup, T., Løwenstein, F. T., Larsen, M. A., Helge, Jørn Wulff, Póvoas, S. C. A. & Aagaard, P., 2020, In: P L o S One. 15, 11, 17 p., e0241359.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial

    Uth, J., Fristrup, B., Sørensen, V., Helge, Eva Wulff, Christensen, M. K., Kjærgaard, J. B., Møller, T. K. T., Mohr, M., Helge, Jørn Wulff, Jørgensen, Niklas Rye, Rørth, M., Vadstrup, E. S. & Krustrup, P., 2020, In: Progress in Cardiovascular Diseases. 63, 6, p. 792-799 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Exercise training results in depot-specific adaptations to adipose tissue mitochondrial function

    Mendham, A. E., Larsen, Steen, George, C., Adams, K., Hauksson, J., Olsson, T., Fortuin-de Smidt, M. C., Nankam, P. A. N., Hakim, O., Goff, L. M., Pheiffer, C. & Goedecke, J. H., 2020, In: Scientific Reports. 10, 1, 14 p., 3785.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Folate stress induces SLX1- and RAD51-dependent mitotic DNA synthesis at the fragile X locus in human cells

    Garribba, L., Bjerregaard, Victoria Alexandra, Gonçalves Dinis, M. M., Özer, Ö., Wu, Wei, Sakellariou, D., Pena-Diaz, J., Hickson, Ian David & Liu, Ying, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 28, p. 16527-16536 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Football as Medicine against type 2 diabetes and metabolic syndrome

    de Sousa, M., Brito, J., Mohr, M., Nassis, G. P., Helge, Jørn Wulff, Pettersen, S. A., Andersen, T. R. & Krustrup, P., 2020, Football as Medicine: Prescribing Football for Global Health Promotion. Krustrup, P. & Parnell, D. (eds.). Routledge, p. 25-40 (Critical Research in Football).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  27. Published

    Frailty Index Status of Canadian Home Care Clients Improves With Exercise Therapy and Declines in the Presence of Polypharmacy

    Larsen, R. T., Turcotte, L. A., Westendorp, Rudi GJ, Langberg, Henning & Hirdes, J. P., 2020, In: Journal of the American Medical Directors Association. 21, 6, p. 766-771 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Freeloading in biomedical research

    Rozing, Maarten Pieter, van Leeuwen, T. N., Reitsma, P. H., Rosendaal, F. R. & Aziz, N. A., 2020, In: Scientometrics. 122, 1, p. 47-55 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Gene–Environment Interplay Between Physical Exercise and Fitness and Depression Symptomatology

    Johnson, W., Mortensen, Erik Lykke & Kyvik, K. O., 2020, In: Behavior Genetics. 50, 5, p. 346-362 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Heterochromatin: an epigenetic point of view in aging

    Lee, J., Kim, E. W., Croteau, D. L. & Bohr, Vilhelm, 2020, In: Experimental & Molecular Medicine. 52, 9, p. 1466-1474 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  31. Published

    Heterotopic Ossification after an Achilles Tendon Rupture Cannot Be Prevented by Early Functional Rehabilitation: A Cohort Study

    Magnusson, Stig Peter, Agergaard, A. S., Couppé, Christian, Svensson, R. B., Warming, S., Krogsgaard, Michael R., Kjær, Michael & Eliasson, P., 2020, In: Clinical Orthopaedics and Related Research. 478, 5, p. 1101-1108 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing

    Macheret, M., Bhowmick, Rahul, Sobkowiak, K., Padayachy, L., Mailler, J., Hickson, Ian David & Halazonetis, T. D., 2020, In: Cell Research. 30, p. 997–1008

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy

    Zheng, Jin, Akbari, M., Schirmer, C., Reynaert, M. L., Loyens, A., Lefebvre, B., Buée, L., Croteau, D. L., Galas, M. C. & Bohr, Vilhelm, 2020, In: Acta Neuropathologica Communications. 8, 1, 23 p., 25.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Histology and Function of the Rectus Abdominis Muscle in Patients With Incisional Hernia

    Jensen, K. K., Oma, E., Kjær, Michael, Jørgensen, Lars Nannestad & Andersen, J. L., 2020, In: Journal of Surgical Research. 253, p. 245-251 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase

    Venegas, A. B., Natsume, T., Kanemaki, M. & Hickson, Ian David, 2020, In: Cell Reports. 31, 3, 20 p., 107533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Inducible deletion of skeletal muscle AMPKα 1 reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

    Hingst, J. R., Kjøbsted, R., Birk, J. B., Jørgensen, N. O., Larsen, M. R., Kido, K., Larsen, J. K., Kjeldsen, S. A. S., Fentz, J., Frøsig, C., Holm, S., Fritzen, A. M., Dohlmann, T. L., Larsen, S., Foretz, M., Viollet, B., Schjerling, P., Overby, P., Halling, J. F., Pilegaard, H. & 2 others, Hellsten, Ylva & Wojtaszewski, Jørgen F P, 2020, In: Molecular Metabolism. 40, 17 p., 101028.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Infant Socioeconomic Position and Quality of Life in Midlife: A 50-Year Follow-Up Study of 2079 Individuals in Denmark

    Hegelund, Emilie Rune, Folker, A. P., Wimmelmann, Cathrine Lawaetz, Just-Østergaard, E., Mortensen, Erik Lykke & Flensborg-Madsen, Trine, 2020, In: Applied Research in Quality of Life. 15, p. 937–951 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours

    Harpelunde Poulsen, K., Nielsen, J. E., Grønkær Toft, B., Joensen, Ulla Nordström, Rasmussen, Lene Juel, Blomberg Jensen, M., Mitchell, R. T., Juul, Anders, Rajpert-De Meyts, E. & Jørgensen, Anders, 2020, In: BMC Cancer. 20, 1, 14 p., 349.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Influence of the integrin alpha-1 subunit and its relationship with high-fat diet upon extracellular matrix synthesis in skeletal muscle and tendon

    Bayer, M. L., Svensson, R. B., Schjerling, P., Williams, A. S., Wasserman, D. H. & Kjær, Michael, 2020, In: Cell and Tissue Research. 381, 1, p. 177-187

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase

    Duan, S., Han, X., Akbari, M., Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6530–6546

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects

    van der Spoel, E., Roelfsema, F., Akintola, A. A., Jansen, S. W., Slagboom, P. E., Westendorp, Rudi GJ, Blauw, G. J., Pijl, H. & van Heemst, D., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 4, p. e1201–e1214 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Key Components of Human Myofibre Denervation and Neuromuscular Junction Stability are Modulated by Age and Exercise

    Søndenbroe, C., Bechshøft, C. J. L., Heisterberg, M. F., Jensen, S. M., Bomme, E., Schjerling, Peter, Karlsen, Anders, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2020, In: Cells. 9, 4, 893.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Long-term exposure to air pollution and stroke incidence: A Danish Nurse cohort study

    Amini, H., Dehlendorff, C., Lim, Y-H., Mehta, A., Jørgensen, J. T., Mortensen, L. H., Westendorp, R., Hoffmann, B., Loft, S., Cole-Hunter, T., Bräuner, E. V., Ketzel, M., Hertel, O., Brandt, J., Solvang Jensen, S., Christensen, J. H., Geels, C., Frohn, L. M., Backalarz, C., Simonsen, M. K. & 1 others, Andersen, Zorana Jovanovic, 2020, In: Environment International. 142, 8 p., 105891.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Low-Grade Inflammation Is Not Present in Former Obese Males but Adipose Tissue Macrophage Infiltration Persists

    Ara, I., Auerbach, P., Larsen, Steen, Mata, E., Stallknecht, Bente Merete, Ploug, Thorkil, Prats Gavalda, Clara & Helge, Jørn Wulff, 2020, In: Biomedicines. 8, 5, 10 p., 123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Macrophage Subpopulations and the Acute Inflammatory Response of Elderly Human Skeletal Muscle to Physiological Resistance Exercise

    Jensen, S. M., Bechshøft, C. J. L., Heisterberg, M. F., Schjerling, P., Andersen, J. L., Kjær, Michael & Mackey, Abigail, 2020, In: Frontiers in Physiology. 11, 15 p., 811.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Maintenance of muscle strength following a one-year resistance training program in older adults

    Gylling, A. T., Bloch-Ibenfeldt, M., Eriksen, C. S., Ziegler, A. K., Wimmelmann, Cathrine Lawaetz, Bækgaard, M., Boraxbekk, CJ, Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, 2020, In: Experimental Gerontology. 139, 111049.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Men Have a Stronger Monocyte-Derived Cytokine Production Response upon Stimulation with the Gram-Negative Stimulus Lipopolysaccharide than Women: A Pooled Analysis Including 15 Study Populations

    Beenakker, K. G. M., Westendorp, Rudi GJ, de Craen, A. J. M., Chen, S., Raz, Y., Ballieux, B. E. P. B., Nelissen, R. G. H. H., Later, A. F. L., Huizinga, T. W., Slagboom, P. E., Boomsma, D. I. & Maier, A. B., 2020, In: Journal of Innate Immunity. 12, p. 142-153 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test

    Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Ritz, C., Larsen, S., Dela, Flemming & Helge, Jørn Wulff, 2020, In: Journal of Applied Physiology. 128, 3, p. 681-687 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Mitochondrial Function in Gilles de la Tourette Syndrome Patients With and Without Intragenic IMMP2L Deletions

    Bjerregaard, Victoria Alexandra, Schönewolf-Greulich, B., Rasmussen, Lene Juel, Desler, Claus & Tümer, Asuman Zeynep, 2020, In: Frontiers in Neurology. 11, 9 p., 163.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Mitochondrial adaptations to high intensity interval training in older females and males

    Chrois, K. M., Dohlmann, T. L., Sogaard, D., Hansen, Camilla Collin, Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2020, In: European Journal of Sport Science. 20, 1, p. 135-145

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Mitochondrial dysfunction in adults after out-of-hospital cardiac arrest

    Wiberg, S., Stride, N., Bro-Jeppesen, J., Holmberg, M. J., Kjærgaard, J., Larsen, Steen, Donnino, M. W., Hassager, Christian & Dela, Flemming, 2020, In: European Heart Journal: Acute Cardiovascular Care. 9, 4, p. S138–S144 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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