Center for Healthy Aging

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  1. Published

    "Sometimes you just have to walk alone"--meanings of emotional support among Danish-born and migrant cancer patients

    Kristiansen, Maria, Tjørnhøj-Thomsen, T. & Krasnik, Allan, 1 Nov 2010, In: Journal of Psychosocial Oncology. 28, 6, p. 699-717 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    'Spreading depression of Leão' and its emerging relevance to acute brain injury in humans

    Lauritzen, Martin & Strong, A. J., 2016, In: Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1553-1570

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    (U)overensstemmelse mellem behandler- og patientvurdering af effekt af gruppeterapi

    Elkjær, H. K., Mortensen, Erik Lykke, Poulsen, Stig Bernt, Kristensen, Ellids Mellerup & Lau, M. E., 2012, In: Matrix. 29, 1, p. 23-38 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif

    Andersen, S. D., Keijzers, G., Rampakakis, E., Engels, K., Luhn, P., El-Shemerly, M., Nielsen, Finn Cilius, Du, Y., May, A., Bohr, Vilhelm, Ferrari, S., Zannis-Hadjopoulos, M., Fu, H. & Rasmussen, Lene Juel, Mar 2012, In: D N A Repair. 11, 3, p. 267-77 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    18F-fluorodeoxyglucose and PET/CT for noninvasive study of exercise-induced glucose uptake in rat skeletal muscle and tendon

    Skovgaard, D., Kjær, Michael, El Ali, Henrik H. & Kjær, Andreas, May 2009, In: European Journal of Nuclear Medicine and Molecular Imaging. 36, 5, p. 859-68 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    2706 km cycling in 2 weeks: effects on cardiac function in 6 elderly male athletes

    Morville, T., Rosenkilde, M., Mattsson, N., Dela, Flemming, Helge, Jørn Wulff & Rasmusen, Hanne K., 2018, In: Physician and Sportsmedicine. 46, 3, p. 263-268 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    3-D ultrastructure and collagen composition of healthy and overloaded human tendon: evidence of tenocyte and matrix buckling

    Pingel, Jessica, Lu, Y., Starborg, T., Fredberg, U., Langberg, Henning, Nedergaard, A., Weis, M., Eyre, D., Kjær, Michael & Kadler, K. E., 9 Feb 2014, In: Journal of Anatomy. 224, 5, p. 548–555 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    3-Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons

    Marosi, K., Kim, S. W., Moehl, K., Scheibye-Knudsen, Morten, Cheng, A., Cutler, R., Camandola, S. & Mattson, M. P., Dec 2016, In: Journal of Neurochemistry. 139, 5, p. 769-781 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    5'-AMP activated protein kinase is involved in the regulation of myocardial ß-oxidative capacity in mice

    Stride, N., Larsen, S., Treebak, Jonas Thue, Hansen, C. N., Hey-Mogensen, M., Speerschneider, T., Jensen, Thomas Elbenhardt, Jeppesen, J., Wojtaszewski, Jørgen F P, Richter, Erik A., Køber, Lars Valeur & Dela, Flemming, 22 Feb 2012, In: Frontiers in Physiology. 3, 7 p., 00033.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

    Lukas, Claudia, Savic, V., Bekker-Jensen, Simon Holst, Doil, C., Neumann, B., Pedersen, R. S., Grøfte, M., Chan, K. L., Hickson, Ian David, Bartek, J. & Lukas, Jiri, 1 Mar 2011, In: Nature Cell Biology. 13, 3, p. 243-53 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice

    Fang, E. F., Palikaras, K., Sun, N., Fivenson, E. M., Spangler, R. D., Kerr, J. S., Cordonnier, S. A., Hou, Y., Dombi, E., Kassahun, H., Tavernarakis, N., Poulton, J., Nilsen, H. & Bohr, Vilhelm, 2017, In: Journal of Visualized Experiments. 129, e56301.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The impact of social relations on the incidence of severe depressive symptoms among infertile women and men

    Lund, Rikke, Sejbæk, C. S., Christensen, Ulla & Schmidt, Lone, 2009, In: Human Reproduction. 24, 11, p. 2810-2820 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Helicobacter pylori infection affects mitochondrial function and DNA repair, thus, mediating genetic instability in gastric cells

    Machado, A. M. D., Desler, C., Boggild, S., Strickertsson, J. A. B., Friis-Hansen, Lennart Jan, Figueiredo, C., Seruca, R. & Rasmussen, Lene Juel, 2013, In: Mechanisms of Ageing and Development. 134, 10, p. 460-466 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity

    Basse, A. L., Agerholm, M., Farup, J., Dalbram, E., Nielsen, J., Ørtenblad, N., Altıntaş, A., Ehrlich, A. M., Krag, T., Bruzzone, S., Dall, M., de Guia, R. M., Jensen, J. B., Møller, A. B., Karlsen, A., Kjær, M., Barrès, R., Vissing, J., Larsen, S., Jessen, N. & 1 others, Treebak, Jonas Thue, 2021, In: Molecular Metabolism. 53, 101271.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside

    Anugula, Sharath, Li, Zhiquan, Li, Yuan, Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, Vilhelm, Desler, Claus, Naviaux, R. K. & Rasmussen, Lene Juel, 2023, In: Heliyon. 9, 6, e17392.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A Biological Age Model Designed for Health Promotion Interventions: Protocol for an Interdisciplinary Study for Model Development

    Husted, Karina Louise Skov, Fogelstrom, M., Hulst, P., Brink-Kjaer, A., Henneberg, K., Sorensen, H. B. D., Dela, Flemming & Helge, Jørn Wulff, 2020, In: JMIR Research Protocols. 9, 10, 13 p., 19209.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis

    Hasan-Olive, M. M., Lauritzen, K. H., Ali, M., Rasmussen, Lene Juel, Storm-Mathisen, J. & Bergersen, L. H., 2019, In: Neurochemical Research. 44, 1, p. 22-37 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A Model for Estimating Biological Age From Physiological Biomarkers of Healthy Aging: Cross-sectional Study

    Husted, Karina Louise Skov, Brink-Kjaer, A., Fogelstrom, M., Hulst, P., Bleibach, A., Henneberg, K., Sorensen, H. B. D., Dela, Flemming, Jacobsen, Jens Christian Brings & Helge, Jørn Wulff, 2022, In: JMIR Aging. 5, 2, 15 p., 35696.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    A Molecular Toolbox to Engineer Site-Specific DNA Replication Perturbation

    Larsen, N. B., Hickson, Ian David & Mankouri, H. W., 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 295-309 15 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  20. Published

    A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression

    Syed, S., Desler, Claus, Rasmussen, Lene Juel & Schmidt, K. H., Dec 2016, In: P L o S Genetics. 12, 12, 28 p., e1006451.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A Psychometric Validation Analysis of Eysenck’s Neuroticism and Extraversion Scales in a Sample of First Time Depressed Patients

    Møller, S. B., Bech, P., Kessing, Lars Vedel, Mortensen, Erik Lykke, Austin, Stephen Fitzgerald & Bukh, J. O. D., 2015, In: Journal of Depression and Anxiety. 4, 4, 6 p., 1000202.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    A Rasch-based validity study of the Harvard Trauma Questionnaire

    Vindbjerg, E., Lohmann, Jessica Mariana Carlsson, Mortensen, Erik Lykke, Makransky, Guido & Nielsen, Tine, 2020, In: Journal of Affective Disorders. 277, p. 697-705 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A Register-Based Study of Occupational Functioning in Non-Psychotic Patients Before and After Psychotherapy

    Fenger, M. M., Poulsen, Stig Bernt, Mortensen, Erik Lykke & Lau, M. E., 2013, In: The Open Psychiatry Journal. 7, p. 1-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A Role for BLM in Double-Strand Break Repair Pathway Choice: Prevention of CtIP/Mre11-Mediated Alternative Nonhomologous End-Joining.

    Grabarz, A., Guirouilh-Barbat, J., Barascu, A., Pennarun, G., Genet, D., Rass, E., Germann, S. M., Bertrand, P., Hickson, Ian David & Lopez, B. S., 17 Oct 2013, In: Cell Reports. 5, 1, p. 21-28 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development

    Specks, J., Lecona, E., Lopez-Contreras, Andres & Fernandez-Capetillo, O., Sep 2015, In: Molecular and Cellular Biology. 35, 17, p. 2910-2917 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

    Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, Vilhelm, Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. & Hickson, Ian David, 24 Jan 2013, In: Chemistry & Biology. 20, 1, p. 55-62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    A Wais Longitudinal Study of Cognitive Development During The Life Span From Ages 50 To 70

    Mortensen, Erik Lykke & Kleven, M., 1 Apr 1993, In: Developmental Neuropsychology. 9, 2, p. 115-130 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    A bidirectional association between cognitive ability in young adulthood and epilepsy: a population-based cohort study

    Osler, Merete, Mortensen, Erik Lykke, Christensen, K. & Okholm, Gunhild Tidemann, 2018, In: International Journal of Epidemiology. 47, 4, p. 1151-1158 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    A century of trends in adult human height

    Damsgaard, Camilla Trab, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Sørensen, Thorkild I.A. & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., 26 Jul 2016, In: eLife. 5, 29 p., e13410.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    A cohort study of leisure time physical activity and depression

    Mikkelsen, S. S., Tolstrup, J. S., Flachs, E. M., Mortensen, Erik Lykke, Schnohr, P. & Flensborg-Madsen, Trine, Dec 2010, In: Preventive Medicine. 51, 6, p. 471-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    A comparison of three methods to measure asthma in epidemiologic studies: results from the Danish National Birth Cohort

    Hansen, S., Strøm, M., Maslova, E., Mortensen, Erik Lykke, Granström, C. & Olsen, Sjurdur F., 2012, In: P L o S One. 7, 5, p. e36328

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    A critical note on Lezak's 'Best performance method' in clinica neuropsychology

    Mortensen, Erik Lykke, Gade, A. & Reinisch, J. M., 1991, In: Journal of Clinical and Experimental Neuropsychology. 13, 2, p. 361-371 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    A critical role for astrocytes in hypercapnic vasodilation in brain

    Howarth, C., Sutherland, B. A., Choi, H. B., Martin, C., Lind, Barbara Lykke, Khennouf, Lila, LeDue, J. M., Pakan, J. M. P., Ko, R. W., Ellis-Davies, G. C. R., Lauritzen, Martin, Sibson, N. R., Buchan, A. M. & MacVicar, B. A., 2017, In: The Journal of Neuroscience. 37, 9, p. 2403-2414 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice

    Petr, Michael Angelo, Alfaras, I., Krawcyzk, M., Bair, W. N., Mitchell, S. J., Morrell, C. H., Studenski, S. A., Price, N. L., Fishbein, K. W., Spencer, R. G., Scheibye-Knudsen, Morten, Lakatta, E. G., Ferrucci, L., Aon, M. A., Bernier, M. & de Cabo, R., 2021, In: eLife. 10, 25 p., e62952.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    A defined human aging phenome

    Andreassen, Søren Norge, Ben Ezra, Michael & Scheibye-Knudsen, Morten, 2019, In: Aging. 11, 15, p. 5786-5806 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome

    Drost, M., Tiersma, Y., Thompson, B. A., Frederiksen, J. H., Keijzers, G., Glubb, D., Kathe, S., Osinga, J., Westers, H., Pappas, L., Boucher, K. M., Molenkamp, S., Zonneveld, J. B., van Asperen, C. J., Goldgar, D. E., Wallace, S. S., Sijmons, R. H., Spurdle, A. B., Rasmussen, L. J., Greenblatt, M. S. & 2 others, de Wind, N. & Tavtigian, S. V., 2019, In: Genetics in Medicine. 21, p. 1486–1496

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    A high carbohydrate diet remains the evidence based choice for elite athletes to optimise performance

    Helge, Jørn Wulff, 1 May 2017, In: Journal of Physiology. 595, 9, p. 2775-2775

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  38. Published

    A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome

    Scheibye-Knudsen, M., Mitchell, S. J., Fang, E. F., Iyama, T., Ward, T., Wang, J., Dunn, C. A., Singh, N., Veith, S., Hasan-Olive, M. M., Mangerich, A., Wilson, M. A., Mattson, M. P., Bergersen, L. H., Cogger, V. C., Warren, A., Le Couteur, D. G., Moaddel, R., Wilson, D. M., Croteau, D. L. & 2 others, De Cabo, R. & Bohr, Vilhelm, 4 Nov 2014, In: Cell Metabolism. 20, 5, p. 840-855 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

    Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    A longitudinal cohort study of intelligence and later hospitalisation with mental disorder

    Mikkelsen, S. S., Flensborg-Madsen, Trine, Eliasen, M. & Mortensen, Erik Lykke, May 2014, In: Comprehensive Psychiatry. 55, 4, p. 912-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    A maximal cycle test with good validity and high repeatability in adults of all ages

    Eriksen, L., Tolstrup, J. S., Larsen, Steen, Grønbæk, M. & Helge, Jørn Wulff, Dec 2014, In: International Journal of Sports Medicine. 35, 14, p. 1184-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

    Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    A new home for the Journal of Cerebral Blood Flow and Metabolism

    Dirnagl, U. & Lauritzen, Martin, Feb 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 2, p. 277

    Research output: Contribution to journal › Editorial › Research › peer-review

  44. Published

    A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

    Luijsterburg, M. S., Acs, K., Ackermann, L., Wiegant, W. W., Bekker-Jensen, Simon Holst, Larsen, D. H., Khanna, K. K., van Attikum, H., Mailand, Niels & Dantuma, N. P., 2012, In: E M B O Journal. 31, 11, p. 2511-27 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    A novel TPR-BEN domain interaction mediates PICH-BEND3 association

    Pitchai, G. P., Kaulich, M., Bizard, A. H., Mesa, Pablo, Yao, Q., Sarlos, K., Streicher, W. W., Nigg, E. A., Montoya, Guillermo & Hickson, Ian David, 2017, In: Nucleic Acids Research. 19, 2, p. 11413–11424

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    A novel antirecombinase gains PARIty

    Mankouri, H. W., Chu, W. K. & Hickson, Ian David, Jan 2012, In: Molecular Cell. 45, 1, p. 6-7 2 p.

    Research output: Contribution to journal › Review › Research › peer-review

  47. Published

    A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function

    Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 3991-4010 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function

    Boutoual, R., Jo, H., Heckenbach, Indra John, Tiwari, R., Kasler, H., Lerner, C. A., Shah, S., Schilling, B., Calvanese, V., Rardin, M. J., Scheibye-Knudsen, Morten & Verdin, E., 2022, In: Scientific Reports. 12, 14804.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    A potential link between early language developmental milestones and personality traits in adulthood

    Flensborg-Madsen, Trine, Wimmelmann, Cathrine Lawaetz & Mortensen, Erik Lykke, 2020, In: International Journal of Behavioral Development. 44, p. 383-392 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    A prospective association between quality of life and risk for cancer

    Flensborg-Madsen, Trine, Johansen, C., Grønbæk, M. & Mortensen, Erik Lykke, 2011, In: European Journal of Cancer. 47, 16, p. 2446-52

    Research output: Contribution to journal › Journal article › Research › peer-review

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