Center for Healthy Aging

  1. Published

    Regional differences in turnover, composition, and mechanics of the porcine flexor tendon

    Zhang, C., Svensson, R. B., Couppé, Christian, Schjerling, P., Skovgaard, D., Kjær, Michael & Magnusson, Stig Peter, 2020, In: Connective Tissue Research. 61, 5, p. 475-484

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Regional collagen turnover and composition of the human patellar tendon

    Zhang, C., Couppé, Christian, Scheijen, J. L. J. M., Schalkwijk, C. G., Kjær, Michael, Magnusson, Stig Peter & Svensson, R. B., 2020, In: Journal of Applied Physiology. 128, 4, p. 884-891

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Comparison of Tenocyte Populations from the Core and Periphery of Equine Tendons

    Zhang, C., Svensson, R. B., Montagna, C., Carstensen, Helena, Buhl, Rikke, Schoof, E. M., Kjær, Michael, Magnusson, Stig Peter & Yeung, C. Y. C., 2020, In: Journal of Proteome Research. 19, 10, p. 4137-4144 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Long-term exposure to air pollution and risk of SARS-CoV-2 infection and COVID-19 hospitalization or death: Danish nationwide cohort study

    Zhang, Jiawei, Lim, Youn-Hee, So, Rina, Jørgensen, J. T., Mortensen, Laust Hvas, Napolitano, George, Cole-Hunter, Thomas, Loft, Steffen, Bhatt, Samir, Hoek, G., Brunekreef, B., Westendorp, Rudi GJ, Ketzel, M., Brandt, J., Lange, Theis, Kølsen-Fisher, T. & Andersen, Zorana Jovanovic, 2023, In: The European respiratory journal. 61, 6, 50 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Histone malonylation is regulated by SIRT5 and KAT2A

    Zhang, R., Bons, J., Scheidemantle, G., Liu, X., Bielska, O., Carrico, C., Rose, J., Heckenbach, Indra John, Scheibye-Knudsen, Morten, Schilling, B. & Verdin, E., 2023, In: iScience. 26, 3, 106193.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Artificial intelligence for aging and longevity research: Recent advances and perspectives

    Zhavoronkov, A., Mamoshina, P., Vanhaelen, Q., Scheibye-Knudsen, Morten, Moskalev, A. & Aliper, A., 2019, In: Ageing Research Reviews. 49, p. 49-66 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells

    Zheng, Jin, Croteau, D. L., Bohr, Vilhelm & Akbari, M., 2019, In: Nucleic Acids Research. 47, 8, p. 4086–4110

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy

    Zheng, Jin, Akbari, M., Schirmer, C., Reynaert, M. L., Loyens, A., Lefebvre, B., Buée, L., Croteau, D. L., Galas, M. C. & Bohr, Vilhelm, 2020, In: Acta Neuropathologica Communications. 8, 1, 23 p., 25.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise

    Ziegler, A. K., Damgaard, A., Mackey, Abigail, Schjerling, Peter, Magnusson, Stig Peter, Olesen, A. T., Kjær, Michael & Schéele, Camilla Charlotte Nielsen, 2019, In: Scientific Reports. 9, 11 p., 12069.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation

    Ziegler, A. K., Jensen, S. M., Schjerling, P., Mackey, Abigail, Andersen, J. L. & Kjær, Michael, 2019, In: Experimental Gerontology. 121, p. 19-32

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Time course for the recovery of physical performance, blood hemoglobin, and ferritin content after blood donation

    Ziegler, A. K., Grand, J., Stangerup, I., Nielsen, H. J., Dela, Flemming, Magnussen, K. & Helge, Jørn Wulff, Apr 2015, In: Transfusion. 55, 4, p. 898–905 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Levothyroxine Treatment and Cardiovascular Outcomes in Older People With Subclinical Hypothyroidism: Pooled Individual Results of Two Randomised Controlled Trials

    Zijlstra, L. E., Jukema, J. W., Westendorp, Rudi GJ, Du Puy, R. S., Poortvliet, R. K. E., Kearney, P. M., O'Keeffe, L., Dekkers, O. M., Blum, M. R., Rodondi, N., Collet, T., Quinn, T. J., Sattar, N., Stott, D. J., Trompet, S., den Elzen, W. P. J., Gussekloo, J. & Mooijaart, S. P., 2021, In: Frontiers in Endocrinology. 12, 8 p., 674841.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Can electrical stimulation enhance effects of a functional training program in hospitalized geriatric patients?

    Zinglersen, A. H., Halsteen, M. B., Kjær, Michael & Karlsen, Anders, Jun 2018, In: Experimental Gerontology. 106, p. 101-108 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Circulating Thyroid Hormone Profile in Response to a Triiodothyronine Challenge in Familial Longevity

    Zutinic, A., Blauw, G. J., Pijl, H., Ballieux, B. E., Westendorp, Rudi GJ, Roelfsema, F. & van Heemst, D., 2020, In: Endocrine Research. 4, 10, 9 p., bvaa117.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Familial Longevity is Associated with an Attenuated Thyroidal Response to Recombinant Human Thyroid Stimulating Hormone

    Zutinic, A., Pijl, H., Ballieux, B. E., Roelfsema, F., Westendorp, Rudi GJ, Blauw, G. J. & van Heemst, D., 1 Jul 2020, In: The Journal of clinical endocrinology and metabolism. 105, 7, p. e2572–e2580 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Familial longevity is associated with lower baseline bone turnover but not differences in bone turnover in response to rhTSH

    Zutinic, A., Roelfsema, F., Pijl, H., Ballieux, B. E., Westendorp, Rudi GJ, Blauw, G. J. & van Heemst, D., 2021, In: Aging. 13, 17, p. 21029-21039 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Trait aggression and trait impulsivity are not related to frontal cortex 5-HT2A receptor binding in healthy individuals

    da Cunha-Bang, S., Stenbæk, D. S., Holst, K., Licht, C. L., Jensen, P. S., Frokjaer, V. G., Mortensen, Erik Lykke & Knudsen, Gitte Moos, 2013, In: Psychiatry Research. 212, 2, p. 125-131 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Grip Work Measurement with the Jamar Dynamometer: Validation of a Simple Equation for Clinical Use

    de Dobbeleer, L., Beyer, I., Hansen, Åse Marie, Molbo, Drude, Mortensen, Erik Lykke, Lund, Rikke & Bautmans, I., 2019, In: Journal of Nutrition, Health and Aging. 23, 2, p. 221-224 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Aerobic and resistance exercise training reverses age-dependent decline in NAD(+) salvage capacity in human skeletal muscle

    de Guia, R. M., Agerholm, M., Nielsen, Thomas Svava, Consitt, L. A., Sogaard, D., Helge, Jørn Wulff, Larsen, Steen, Brandauer, J., Houmard, J. A. & Treebak, Jonas Thue, 2019, In: Physiological Reports. 7, 12, 15 p., e14139.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial

    de Montmollin, M., Feller, M., Beglinger, S., McConnachie, A., Aujesky, D., Collet, T., Ford, I., Gussekloo, J., Kearney, P. M., McCarthy, V. J. C., Mooijaart, S., Poortvliet, R. K. E., Quinn, T., Stott, D. J., Watt, Torquil, Westendorp, Rudi GJ, Rodondi, N. & Bauer, D. C., 2 Jun 2020, In: Annals of Internal Medicine. 172, 11, p. 709-716 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Football as Medicine against type 2 diabetes and metabolic syndrome

    de Sousa, M., Brito, J., Mohr, M., Nassis, G. P., Helge, Jørn Wulff, Pettersen, S. A., Andersen, T. R. & Krustrup, P., 2020, Football as Medicine: Prescribing Football for Global Health Promotion. Krustrup, P. & Parnell, D. (eds.). Routledge, p. 25-40 (Critical Research in Football).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  22. Published

    Mitochondrial helicases and mitochondrial genome maintenance

    de Souza-Pinto, N. C., Aamann, M. D., Kulikowicz, T., Stevnsner, T. V. & Bohr, Vilhelm, 2010, In: Mechanisms of Ageing and Development. 131, 7-8, p. 503-10 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells

    de Souza-Pinto, N. C., Maynard, S., Hashiguchi, K., Hu, J., Muftuoglu, M. & Bohr, Vilhelm, Aug 2009, In: Molecular and Cellular Biology. 29, 16, p. 4441-54 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Mitochondrial dysfunction induced by variation in the non-coding genome – A proposed workflow to improve diagnostics

    du Mee, D. J. M., Bak, M., Østergaard, Elsebet & Rasmussen, Lene Juel, 2020, In: Mitochondrion. 53, p. 255-259

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Neighborhood perceptions and allostatic load: Evidence from Denmark

    van Deurzen, I., Rod, Naja Hulvej, Christensen, Ulla, Hansen, Åse Marie, Lund, Rikke & Dich, N., Jul 2016, In: Health & Place. 40, p. 1-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Effect of APOE ε4 allele on survival and fertility in an adverse environment

    van Exel, E., Koopman, J. J. E., Bodegom, D. V., Meij, J. J., Knijff, P. D., Ziem, J. B., Finch, C. E. & Westendorp, Rudi GJ, 6 Jul 2017, In: PLOS ONE. 12, 7, p. 1-13 13 p., e0179497.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Effects of intranasal insulin application on the hypothalamic BOLD response to glucose ingestion

    van Opstal, A. M., Akintola, A. A., Elst, M. V. D., Westendorp, Rudi GJ, Pijl, H., van Heemst, D. & van der Grond, J., 17 Oct 2017, In: Scientific Reports. 7, p. 1-7 7 p., 13327.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Thyroid Stimulating Hormone and Bone Mineral Density: Evidence From a Two-Sample Mendelian Randomization Study and a Candidate Gene Association Study

    van Vliet, N. A., Noordam, R., van Klinken, J. B., Westendorp, Rudi GJ, Bassett, J. D., Williams, G. R. & van Heemst, D., 2018, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 33, 7, p. 1318-1325 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Thyroid status and mortality in nonagenarians from long-lived families and the general population

    van Vliet, N. A., van der Spoel, E., Beekman, M., Slagboom, P. E., Blauw, G. J., Gussekloo, J., Westendorp, Rudi GJ & van Heemst, D., Oct 2017, In: Aging. 9, 10, p. 2223—2234 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Early and extraordinary peaks in physical performance come with a longevity cost

    van de Vijver, P. L., van Bodegom, D. & Westendorp, Rudi GJ, 19 Aug 2016, In: Aging. 8, 8, p. 1822-1829 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study

    van der Spoel, E., Rozing, M. P., Houwing-Duistermaat, J. J., Slagboom, P. E., Beekman, M., de Craen, A. J. M., Westendorp, Rudi GJ & van Heemst, D., 12 Nov 2015, In: Aging. 7, 11, p. 956–963 8 p., PMC4694065.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects

    van der Spoel, E., Roelfsema, F., Akintola, A. A., Jansen, S. W., Slagboom, P. E., Westendorp, Rudi GJ, Blauw, G. J., Pijl, H. & van Heemst, D., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 4, p. e1201–e1214 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Growth hormone secretion is diminished and tightly controlled in humans enriched for familial longevity

    van der Spoel, E., Jansen, S. W., Akintola, A. A., Ballieux, B. E., Cobbaert, C. M., Slagboom, P. E., Blauw, G. J., Westendorp, Rudi GJ, Pijl, H., Roelfsema, F. & van Heemst, D., Dec 2016, In: Aging Cell. 15, 6, p. 1126–1131 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Familial Longevity Is Not Associated with Major Differences in the Hypothalamic–Pituitary–Gonadal Axis in Healthy Middle-Aged Men

    van der Spoel, E., Roelfsema, F., Jansen, S. W., Akintola, A. A., Ballieux, B. E., Cobbaert, C. M., Blauw, G. J., Slagboom, P. E., Westendorp, Rudi GJ, Piji, H. & van Heemst, D., 9 Nov 2016, In: Frontiers in Endocrinology. 7, p. 1-7 7 p., 143.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Rising rural body-mass index is the main driver of the global obesity epidemic in adults

    Ängquist, Lars, Baker, J. L., Damsgaard, Camilla Trab, Eliasen, M., Linneberg, Allan René, Michaelsen, Kim F., Molbo, Drude, Mortensen, Erik Lykke, Sørensen, Thorkild I.A., Jørgensen, T., Tang Møllehave, L., Thuesen, B. H., Osler, Merete & NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C., 2019, In: Nature. 569, 7755, p. 260-264 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  36. Published

    Thyroid Function Within the Normal Range and Risk of Coronary Heart Disease: An Individual Participant Data Analysis of 14 Cohorts

    Åsvold, B. O., Vatten, L. J., Bjøro, T., Bauer, D. C., Bremner, A., Cappola, A. R., Ceresini, G., den Elzen, W. P. J., Ferrucci, L., Franco, O. H., Franklyn, J. A., Gussekloo, J., Iervasi, G., Imaizumi, M., Kearney, P. M., Khaw, K-T., Maciel, R. M. B., Newman, A. B., Peeters, R. P., Psaty, B. M. & 10 others, Razvi, S., Sgarbi, J. A., Stott, D. J., Trompet, S., Vanderpump, M. P. J., Völzke, H., Walsh, J. P., Westendorp, Rudi GJ, Rodondi, N. & Thyroid Studies Collaboration, T. S. C., Jun 2015, In: J A M A Internal Medicine. 175, 6, p. 1037-47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism

    Özer, Ö., Bhowmick, Rahul, Liu, Ying & Hickson, Ian David, 2018, In: OncoTarget. 9, 22, p. 15836-15846 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Pathways for maintenance of telomeres and common fragile sites during DNA replication stress

    Özer, Ö. & Hickson, Ian David, 2018, In: Open Biology. 8, 4, 11 p., 180018.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Mental vulnerability as a risk factor for depression: a prospective cohort study in Denmark

    Østergaard, D., Dalton, S. O., Bidstrup, P. E., Poulsen, A. H., Frederiksen, K. S., Eplov, L. F., Johansen, C. & Mortensen, Erik Lykke, 2012, In: International Journal of Social Psychiatry. 58, 3, p. 306-14 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    RNF8 and RNF168 but not HERC2 are required for DNA damage-induced ubiquitylation in chicken DT40 cells

    Østergaard, Vibe Hallundbæk, Pentzold, C., Pedersen, R. T., Iosif, S., Alpi, A., Bekker-Jensen, Simon Holst, Mailand, Niels & Lisby, Michael, 2012, In: D N A Repair. 11, 11, p. 892–905 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

    NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., Damsgaard, Camilla Trab, Michaelsen, Kim F., Afzal, Shoaib, Ängquist, Lars, Bojesen, Stig Egil, Frikke-Schmidt, Ruth, Molbo, Drude, Mortensen, Erik Lykke, Nordestgaard, Børge, Sørensen, Thorkild I.A. & Varbo, A., 2021, In: eLife. 10, 35 p., e60060.

    Research output: Contribution to journalJournal articleResearchpeer-review

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