Center for Healthy Aging

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  1. 2022
  2. Published

    Social relations and contact with general practitioner in a middle-aged Danish population: a prospective register- and survey-based cohort study

    Mikkelsen, A. S. B., Lund, Rikke, Siersma, Volkert Dirk, Jørgensen, Terese Sara Høj, Christensen, Ulla & Kristiansen, Maria, 2022, In: BMC Health Services Research. 22, 481, 481.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders

    Mkrtchyan, Garik, Veviorskiy, A., Izumchenko, E., Shneyderman, A., Pun, F. W., Ozerov, I. V., Aliper, A., Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2022, In: Cell Death and Disease. 13, 11, 999.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Autophagy guards tendon homeostasis

    Montagna, C., Svensson, R. B., Bayer, M. L., Rizza, S., Maiani, E., Yeung, Ching-Yan Chloé, Filomeni, G. & Kjær, Michael, 2022, In: Cell Death and Disease. 13, 4, 402.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

    The European Hereditary Tumour Group (EHTG) and the International Mismatch Repair Consortium (IMRC), T. E. H. T. G. (. A. T. I. M. R. C. (., 2022, In: Hereditary Cancer in Clinical Practice. 20, 36.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Chronicity of posttraumatic stress disorder and comorbid pain as predictors of treatment response for trauma-affected refugees

    Nordbrandt, M. S., Vindbjerg, E., Mortensen, Erik Lykke & Lohmann, Jessica Mariana Carlsson, 2022, In: Journal of Traumatic Stress. 35, 5, p. 1393-1404

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Challenges and lessons learnt from conducting a health survey in an ethnically diverse population

    Nygaard, Siv Steffen, Srivarathan, Abirami, Mathisen, J., Kristiansen, Maria, Christensen, Ulla, Kvorning, M. F. & Lund, Rikke, 2022, In: Scandinavian Journal of Public Health. 50, 7, p. 995-1006 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Antidepressant effects of a psychedelic experience in a large prospective naturalistic sample

    Nygart, V. A., Pommerencke, L. M., Haijen, E., Kettner, H., Kaelen, M., Mortensen, Erik Lykke, Nutt, D. J., Carhart-Harris, R. L. & Erritzoe, D., 2022, In: Journal of Psychopharmacology. 36, 8, p. 932-942 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors

    Pladevall Morera, David, Castejón-Griñán, M., Aguilera, P., Gaardahl, K., Ingham, Andreas, Brosnan-Cashman, J. A., Meeker, A. K. & Lopez-Contreras, Andres, 2022, In: Cancers. 14, 7, 1790.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary

    Schmauck-Medina, T., Molière, A., Lautrup, S., Zhang, J., Chlopicki, S., Madsen, H. B., Cao, S., Soendenbroe, C., Mansell, E., Vestergaard, M. B., Li, Z., Shiloh, Y., Opresko, P. L., Egly, J. M., Kirkwood, T., Verdin, E., Bohr, V. A., Cox, L. S., Stevnsner, T., Rasmussen, L. J. & 1 others, Fang, E. F., 2022, In: Aging. 14, 16, p. 6829-6839 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    Development of a fiber-based microfluidic flow cytometry platform using viscoelastic fluids for polydisperse particle suspensions

    Serhatlioglu, M., Jensen, E. A., Niora, M., Hansen, A. T., Nielsen, Christian Friberg, Theresia Jansman, M. M., Hosta-Rigau, L., Dziegiel, Morten Hanefeld, Berg-Sørensen, K., Hickson, Ian David & Kristensen, A., 2022, In: Proceedings of SPIE - The International Society for Optical Engineering. 12198, 9 p., 1219802.

    Research output: Contribution to journal › Conference article › Research › peer-review

  12. Published

    Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation

    Silva, J., Alkan, F., Ramalho, S., Snieckute, Goda, Prekovic, S., Garcia, A. K., Hernández-Pérez, S., van der Kammen, R., Barnum, D., Hoekman, L., Altelaar, M., Zwart, W., Suijkerbuijk, S. J. E., Bekker-Jensen, Simon Holst & Faller, W. J., 2022, In: Nature Communications. 13, 1, 4492.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Long-term exposure to air pollution and mortality in a Danish nationwide administrative cohort study: Beyond mortality from cardiopulmonary disease and lung cancer

    So, R., Andersen, Z. J., Chen, J., Stafoggia, M., de Hoogh, K., Katsouyanni, K., Vienneau, D., Rodopoulou, S., Samoli, E., Lim, Y-H., Jørgensen, J. T., Amini, H., Cole-Hunter, T., Mahmood Taghavi Shahri, S., Maric, M., Bergmann, M., Liu, S., Azam, S., Loft, S., Westendorp, R. G. J. & 13 others, Mortensen, Laust Hvas, Bauwelinck, M., Klompmaker, J. O., Atkinson, R., Janssen, N. A. H., Oftedal, B., Renzi, M., Forastiere, F., Strak, M., Thygesen, L. C., Brunekreef, B., Hoek, G. & Mehta, A. J., 2022, In: Environment International. 164, 107241.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Preserved stem cell content and innervation profile of elderly human skeletal muscle with lifelong recreational exercise

    Soendenbroe, C., Dahl, C. L., Meulengracht, C., Tamáš, M., Svensson, R. B., Schjerling, Peter, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2022, In: The Journal of Physiology. 600, 8, p. 1969-1989

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    CNOT6: A Novel Regulator of DNA Mismatch Repair

    Song, P., Liu, S., Liu, D., Keijzers, G., Bakula, Daniela Janina, Duan, S., de Wind, N., Ye, Z., Vakhrushev, Sergey, Scheibye-Knudsen, Morten & Rasmussen, Lene Juel, 2022, In: Cells. 11, 3, 521.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    PICH acts as a force-dependent nucleosome remodeler

    Spakman, D., Clement, T. V. M., Biebricher, A. S., King, G. A., Singh, Manika Indrajit, Hickson, Ian David, Peterman, E. J. G. & Wuite, G. J. L., 2022, In: Nature Communications. 13, 7277.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    School performance in Danish children exposed to maternal type 1 diabetes in utero: A nationwide retrospective cohort study

    Spangmose, A. L., Skipper, N., Knorr, S., Gundersen, T. W., Jensen, Rikke Bodin Beck, Damm, Peter, Mortensen, Erik Lykke, Pinborg, Anja, Svensson, Jannet & Clausen, Tine Dalsgaard, 2022, In: PLoS Medicine. 19, 4 April, 14 p., e1003977.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The association between social integration and neighborhood dissatisfaction and unsafety: a cross‑sectional survey study among social housing residents in Denmark

    Srivarathan, Abirami, Kristiansen, Maria, Jørgensen, Terese Sara Høj & Lund, Rikke, 2022, In: Archives of Public Health. 80, 11 p., 190.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies

    Syrogiannouli, L., Wildisen, L., Meuwese, C., Bauer, D. C., Cappola, A. R., Gussekloo, J., den Elzen, W. P. J., Trompet, S., Westendorp, R. G. J., Jukema, J. W., Ferrucci, L., Ceresini, G., Åsvold, B. O., Chaker, L., Peeters, R. P., Imaizumi, M., Ohishi, W., Vaes, B., Völzke, H., Sgarbi, J. A. & 7 others, Walsh, J. P., Dullaart, R. P. F., Bakker, S. J. L., Iacoviello, M., Rodondi, N., Del Giovane, C. & for the Thyroid Studies Collaboration, F. T. T. S. C., 2022, In: Frontiers in Psychiatry. 13, 774251.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Leadership behaviours and health-related early exit from employment: a prospective cohort study of 55 364 employees

    Sørensen, Kathrine, Sørensen, J. K., Andersen, L. L., Eskildsen Bruun, J., Conway, Paul Maurice, Framke, E., Madsen, I. E. H., Nielsen, H. B., Nordentoft, M., Seeberg, K. G. V. & Rugulies, Reiner Ernst, 2022, In: European Journal of Public Health. 32, 5, p. 709–715 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Human derived tendon cells contribute to myotube formation in vitro

    Tsuchiya, Y., Bayer, M. L., Schjerling, Peter, Soendenbroe, C. & Kjær, Michael, 2022, In: Experimental Cell Research. 417, 1, 113164.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants

    Vohra, Rupali, Sanz-Morello, B., Tams, A. L. M., Mouhammad, Zaynab Ahmad, Freude, Kristine, Hannibal, Jens, Aldana, Blanca, Bergersen, L. H. & Kolko, Miriam, 2022, In: Cells. 11, 13, 2098.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Circadian regulation of protein cargo in extracellular vesicles

    Yeung, Ching-Yan Chloé, Dondelinger, F., Schoof, E. M., Georg, B., Lu, Y., Zheng, Z., Zhang, J., Hannibal, Jens, Fahrenkrug, J. & Kjær, Michael, 2022, In: Science Advances. 8, 14, 13 p., eabc9061.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2021
  25. Published

    Mechanical properties and UTE-T2* in Patellar tendinopathy: The effect of load magnitude in exercise-based treatment

    Agergaard, A. S., Svensson, R. B., Høffner, Rikke, Hansen, P., Couppé, Christian, Kjær, Michael & Magnusson, Stig Peter, 2021, In: Scandinavian Journal of Medicine and Science in Sports. 31, 10, p. 1981-1990

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    UTE T2* mapping of tendinopathic patellar tendons: an MRI reproducibility study

    Agergaard, A. S., Malmgaard-Clausen, N. M., Svensson, R. B., Nybing, J. D., Boesen, Mikael Ploug, Kjær, Michael, Magnusson, Stig Peter & Hansen, P., 2021, In: Acta Radiologica. 62, 2, p. 215-224 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    How Do We Explore Heterogeneity in Turnover of Musculoskeletal Proteins?

    Agergaard, J. & Kjær, Michael, 2021, In: Function. 2, 4, 2 p., 034.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Cytosolic self-DNA—A potential source of chronic inflammation in aging

    Akbari, M., Shanley, D. P., Bohr, Vilhelm & Rasmussen, Lene Juel, 2021, In: Cells. 10, 12, 3544.

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    Long-Term Exposure to Road Traffic Noise and Air Pollution, and Incident Atrial Fibrillation in the Danish Nurse Cohort

    Andersen, Z. J., Cramer, J., Jørgensen, J. T., Dehlendorff, C., Amini, H., Mehta, A., Cole-Hunter, T., Mortensen, L. H., Westendorp, R., So, R., Li, S., Hoffmann, B., Loft, S., Bräuner, E. V., Ketzel, M., Hertel, O., Brandt, J., Jensen, S. S., Christensen, J. H., Geels, C. & 4 others, Frohn, L. M., Backalarz, C., Simonsen, M. K. & Lim, Youn-Hee, Aug 2021, In: Environmental Health Perspectives. 129, 8, 87002.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Two genetic analyses to elucidate causality between body mass index and personality

    Arumäe, K., Briley, D., Colodro-Conde, L., Mortensen, Erik Lykke, Jang, K., Ando, J., Kandler, C., Sørensen, Thorkild I.A., Dagher, A., Mõttus, R. & Vainik, U., 2021, In: International Journal of Obesity. 45, p. 2244–2251 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Stress management versus cognitive restructuring in trauma-affected refugees — A follow-up study on a pragmatic randomised trial

    Barhoma, M., Sonne, C., Lommen, M. J. J., Mortensen, Erik Lykke & Lohmann, Jessica Mariana Carlsson, 2021, In: Journal of Affective Disorders. 294, p. 628-637 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity

    Basse, A. L., Agerholm, M., Farup, J., Dalbram, E., Nielsen, J., Ørtenblad, N., Altıntaş, A., Ehrlich, A. M., Krag, T., Bruzzone, S., Dall, M., de Guia, R. M., Jensen, J. B., Møller, A. B., Karlsen, A., Kjær, M., Barrès, R., Vissing, J., Larsen, S., Jessen, N. & 1 others, Treebak, Jonas Thue, 2021, In: Molecular Metabolism. 53, 101271.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Chronic Sequelae After Muscle Strain Injuries: Influence of Heavy Resistance Training on Functional and Structural Characteristics in a Randomized Controlled Trial

    Bayer, M. L., Hoegberget-Kalisz, M., Svensson, R. B., Hjortshoej, M. H., Olesen, J. L., Nybing, J. D., Boesen, Mikael Ploug, Magnusson, Stig Peter & Kjær, Michael, 2021, In: American Journal of Sports Medicine. 49, 10, p. 2783-2794 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Exposure to ultrafine particles while walking or bicycling during COVID-19 closures: A repeated measures study in Copenhagen, Denmark

    Bergmann, Marie, Andersen, Zorana Jovanovic, Amini, H., Ellermann, T., Hertel, O., Lim, Youn-Hee, Loft, Steffen, Mehta, A., Westendorp, Rudi GJ & Cole-Hunter, Thomas, 2021, In: Science of the Total Environment. 791, 9 p., 148301.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Longevity medicine: upskilling the physicians of tomorrow

    Bischof, E., Scheibye-Knudsen, Morten, Siow, R. & Moskalev, A., 2021, In: The Lancet Healthy Longevity. 2, 4, p. e187-e188

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  36. Published

    Asthma-like symptoms in young children increase the risk of COPD

    Bisgaard, H., Nørgaard, S., Sevelsted, A., Chawes, Bo Lund Krogsgaard, Stokholm, Jakob, Mortensen, Erik Lykke, Ulrik, Charlotte Suppli & Bønnelykke, Klaus, 2021, In: Journal of Allergy and Clinical Immunology. 147, 2, p. 569-576 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Effects of football fitness training on lymphedema and upper-extremity function in women after treatment for breast cancer: A randomized trial

    Bloomquist, K., Krustrup, P., Fristrup, B., Sørensen, V., Helge, Jørn Wulff, Helge, Eva Wulff, Soelberg Vadstrup, E., Rørth, M., Hayes, S. C. & Uth, J., 2021, In: Acta Oncologica. 60, 3, p. 392-400 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Associations of loneliness and social isolation with physical and mental health among adolescents and young adults

    Christiansen, J., Qualter, P., Friis, K., Pedersen, S. S., Lund, Rikke, Andersen, C. M., Bekker-Jeppesen, M. & Lasgaard, M., 2021, In: Perspectives in Public Health. 141, 4, p. 226-236 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Depleted myocardial coenzyme Q10 in cavalier king charles spaniels with congestive heart failure due to myxomatous mitral valve disease

    Christiansen, L. B., Reimann, Maria Josefine, Schou-Pedersen, A. M. V., Larsen, Steen, Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Antioxidants. 10, 2, p. 1-13 13 p., 161.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected

    Christiansen, L. B., Dohlmann, T. L., Ludvigsen, T. P., Parfieniuk, E., Ciborowski, M., Szczerbinski, L., Kretowski, A., Desler, Claus, Tiano, L., Orlando, P., Martinussen, Torben, Olsen, Lisbeth Høier & Larsen, Steen, 2021, In: Scientific Reports. 11, 15 p., 2167.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Lifetime psychiatric hospital diagnoses among 8,412 Danish men registered in an outpatient alcohol clinic

    Christoffersen, L. A. N., Mortensen, Erik Lykke, Osler, Merete, Sørensen, H. J., Becker, U. & Flensborg-Madsen, Trine, 2021, In: Brain and Behavior. 11, 3, 13 p., e02004.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Outdoor Light at Night and Breast Cancer Incidence in the Danish Nurse Cohort

    Clarke, Rebecca B, Amini, H., James, P., von Euler-Chelpin, My Catarina, Jørgensen, J. T., Mehta, A., Cole-Hunter, Thomas, Westendorp, Rudi GJ, Mortensen, Laust Hvas, Loft, Steffen, Brandt, J., Hertel, O., Ketzel, M., Backalarz, C., Andersen, Zorana Jovanovic & Lim, Youn-Hee, 2021, In: Environmental Research. 194, 110631.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Reablement through time and space: A scoping review of how the concept of ‘reablement’ for older people has been defined and operationalised

    Clotworthy, Amy, Kusumastuti, S. & Westendorp, Rudi GJ, 15 Jan 2021, In: BMC Geriatrics. 21, 16 p., 61.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Antecedents of workplace bullying among employees in Germany: Five-year lagged effects of job demands and job resources

    Conway, Paul Maurice, Burr, H., Rose, U., Clausen, T. & Balducci, C., 1 Oct 2021, In: International Journal of Environmental Research and Public Health. 18, 20, 13 p., 10805.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Habitual side-specific loading leads to structural, mechanical, and compositional changes in the patellar tendon of young and senior lifelong male athletes

    Couppé, Christian, Svensson, R. B., Skovlund, S. V., Jensen, Jacob Kildevang, Eriksen, C. S., Malmgaard-Clausen, N. M., Nybing, J. D., Kjær, Michael & Magnusson, Stig Peter, 2021, In: Journal of Applied Physiology. 131, 4, p. 1187-1199

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes

    Dall, M., Hassing, Anna Skab, Niu, Lili, Nielsen, Thomas Svava, Ingerslev, L. R., Sulek, K., Trammell, Sam, Gillum, M. P., Barrès, Romain, Larsen, Steen, Poulsen, Steen Seier, Mann, Matthias, Ørskov, Cathrine & Treebak, Jonas Thue, 2021, In: Journal of Biological Chemistry. 297, 6, 26 p., 101388.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Olfactory dysfunction in aging and neurodegenerative diseases

    Dan, X., Wechter, N., Gray, S., Mohanty, J. G., Croteau, D. L. & Bohr, Vilhelm, 2021, In: Ageing Research Reviews. 70, 101416.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    Right-left asymmetry in corticospinal tract microstructure and dexterity are uncoupled in late adulthood

    Demnitz, N., Madsen, K. S., Johnsen, L. K., Kjær, Michael, Boraxbekk, CJ & Siebner, Hartwig Roman, 2021, In: NeuroImage. 240, 118405.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Loss of Ambra1 promotes melanoma growth and invasion

    Di Leo, L., Bodemeyer, V., Bosisio, F. M., Claps, G., Carretta, M., Rizza, S., Faienza, F., Frias, A., Khan, S., Bordi, M., Pacheco, M. P., Di Martino, J., Bravo-Cordero, J. J., Daniel, C. J., Sears, R. C., Donia, M., Madsen, D. H., Guldberg, P., Filomeni, G., Sauter, T. & 3 others, Robert, C., de Zio, Daniela & Cecconi, F., 2021, In: Nature Communications. 12, 1, p. 2550 2550.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration

    Durhuus, J. A., Rozing, Maarten Pieter, Nielsen, M. K., Molbech, C. R., Keijzers, G., Scheibye-Knudsen, Morten, Rasmussen, Lene Juel, Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2021, In: Scientific Reports. 11, 1, 8226.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Six weeks of high intensity cycle training reduces H2O2 emission and increases antioxidant protein levels in obese adults with risk factors for type 2 diabetes

    Flensted-Jensen, Mathias, Gram, M., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2021, In: Free Radical Biology & Medicine. 173, p. 1-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Education and adolescent cognitive ability as predictors of dementia in a cohort of Danish men

    Foverskov, Else, Glymour, M. M., Mortensen, Erik Lykke, Osler, Merete, Okholm, Gunhild Tidemann & Lund, Rikke, 2021, In: PLoS ONE. 15, 8, 13 p., 0235781.

    Research output: Contribution to journal › Journal article › Research › peer-review

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