Center for Healthy Aging

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  1. 2020
  2. Published

    Cellular senescence and chronological age in various human tissues: A systematic review and meta-analysis

    Tuttle, C. S. L., Waaijer, M. E. C., Slee-Valentijn, M. S., Stijnen, T., Westendorp, Rudi GJ & Maier, A. B., 2020, In: Aging Cell. 19, 2, 11 p., e13083.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Circulating Thyroid Hormone Profile in Response to a Triiodothyronine Challenge in Familial Longevity

    Zutinic, A., Blauw, G. J., Pijl, H., Ballieux, B. E., Westendorp, Rudi GJ, Roelfsema, F. & van Heemst, D., 2020, In: Endocrine Research. 4, 10, 9 p., bvaa117.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Cognitive Ability in Midlife and Labor Market Participation Among Older Workers: Prospective Cohort Study With Register Follow-up

    Sundstrup, E., Hansen, Åse Marie, Mortensen, Erik Lykke, Poulsen, O. M., Clausen, T., Rugulies, Reiner Ernst, Møller, Anne & Andersen, L. L., 2020, In: Safety and Health at Work. 11, p. 291-300 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Comparison of Tenocyte Populations from the Core and Periphery of Equine Tendons

    Zhang, C., Svensson, R. B., Montagna, C., Carstensen, Helena, Buhl, Rikke, Schoof, E. M., Kjær, Michael, Magnusson, Stig Peter & Yeung, C. Y. C., 2020, In: Journal of Proteome Research. 19, 10, p. 4137-4144 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Crowdsourcing Hypothesis Tests: Making transparent how design choices shape research results

    Crowdsourced Hypothesis Tests Collaboration, C. H. T. C., 2020, In: Psychological Bulletin. 146, 5, p. 451-479 29 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells

    Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, R. I., Aldana, Blanca, Desler, Claus, Rasmussen, Lene Juel, Sustarsic, E. G., Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In: Frontiers in Immunology. 11, 22 p., 1968.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    DNA damage invokes mitophagy through a pathway involving Spata18

    Dan, X., Babbar, M., Moore, A., Wechter, N., Tian, J., Mohanty, J. G., Croteau, D. L. & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6611-6623 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Discovering correlates of age-related decline in a healthy late-midlife male birth cohort

    Zarnani, K., Smith, S. M., Alfaro-Almagro, F., Fagerlund, Birgitte, Lauritzen, Martin, Rostrup, E. & Nichols, T. E., 2020, In: Aging. 12, 17, p. 16709—16743 35 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Distinct trajectories of long-term symptom severity in pediatric obsessive-compulsive disorder during and after stepped-care treatment

    Jensen, S., Højgaard, D. R. M. A., Hybel, K. A., Mortensen, Erik Lykke, Skarphedinsson, G., Melin, K., Ivarsson, T., Nissen, J. B., Weidle, B., Valderhaug, R., Torp, N. C., Dahl, K., Compton, S. & Thomsen, P. H., 2020, In: Journal of Child Psychology and Psychiatry. 61, 9, p. 969-978 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Do we know the effects of colorectal cancer screening? A short communication on selective uptake and differential effects of colorectal cancer screening in Scandinavia

    Pallesen, Anna Vera Jørring, Herrstedt, Jørn, Westendorp, Rudi GJ, Mortensen, Laust Hvas & Kristiansen, Maria, 2020, In: Scandinavian Journal of Public Health. 49, 8, p. 841-844 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Does Midlife Forgetfulness Influence Positive and Negative Aspects of Social Relations at Work? Results from the Danish Working Environment Cohort Study

    Ishtiak-Ahmed, K., Hansen, Åse Marie, Mortensen, Erik Lykke, Garde, Anne Helene, Grynderup, M. B., Gyntelberg, F., Islamoska, S., Lund, Rikke, Phung, T. K. T., Waldemar, Gunhild & Nabe-Nielsen, Kirsten, 2020, In: Journal of Occupational and Environmental Medicine. 62, 9, p. 738-745 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

    Fontana, D., Mauri, M., Renso, R., Docci, M., Crespiatico, I., Røst, L. M., Jang, M., Niro, A., D’aliberti, D., Massimino, L., Bertagna, M., Zambrotta, G., Bossi, M., Citterio, S., Crescenzi, B., Fanelli, F., Cassina, V., Corti, R., Salerno, D., Nardo, L. & 10 others, Chinello, C., Mantegazza, F., Mecucci, C., Magni, F., Cavaletti, G., Bruheim, P., Rea, D., Larsen, Steen, Gambacorti-passerini, C. & Piazza, R., 2020, In: Nature Communications. 11, 1, 16 p., 5938.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Early Growth Response Genes Increases Rapidly After Mechanical Overloading and Unloading in Tendon Constructs

    Herchenhan, A., Dietrich-Zagonel, F., Schjerling, P., Kjær, Michael & Eliasson, P., 2020, In: Journal of Orthopaedic Research. 38, 1, p. 173-181

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Early development of tendinopathy in humans: Sequence of pathological changes in structure and tissue turnover signaling

    Tran, P. H. T., Malmgaard-Clausen, N. M., Puggaard, R. S., Svensson, R. B., Nybing, J. D., Hansen, P., Schjerling, P., Zinglersen, A. H., Couppé, Christian, Boesen, Mikael Ploug, Magnusson, Stig Peter & Kjær, Michael, 2020, In: FASEB Journal. 34, 1, p. 776-788 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Early life predictors of intelligence in young adulthood and middle age

    Flensborg-Madsen, Trine, Eriksen, H. F. & Mortensen, Erik Lykke, 2020, In: PLoS ONE. 15, 1, 15 p., e0228144.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Economic hardship over twenty-two consecutive years of adult life and markers of early ageing: physical capability, cognitive function and inflammation

    Foverskov, Else, Petersen, G. L., Pedersen, J. L. M., Rod, Naja Hulvej, Mortensen, Erik Lykke, Bruunsgaard, H. & Lund, Rikke, 2020, In: European Journal of Ageing. 17, p. 55-67 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Effect of Platelet-Rich Plasma on Nonsurgically Treated Acute Achilles Tendon Ruptures: A Randomized, Double-Blinded Prospective Study

    Boesen, A. P., Boesen, M. I., Hansen, R., Barfod, Kristoffer Weisskirchner, Lenskjold, A., Malliaras, P. & Langberg, Henning, 2020, In: American Journal of Sports Medicine. 48, 9, p. 2268-2276 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Effect of Thyroid Hormone Therapy on Fatigability in Older Adults with Subclinical Hypothyroidism: A Nested Study within a Randomized Placebo-Controlled Trial

    Stuber, M. J., Moutzouri, E., Feller, M., Del Giovane, C., Bauer, D. C., Blum, M. R., Collet, T. H., Gussekloo, J., Mooijaart, S. P., McCarthy, V. J. C., Aujesky, D., Westendorp, Rudi GJ, Stott, D. J., Glynn, N. W., Kearney, P. M., Rodondi, N. & Newman, A., 2020, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 75, 9, p. e89-e94 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Effects of small-sided recreational team handball training on mechanical muscle function, body composition and bone mineralization in untrained young adults - A randomized controlled trial

    Fristrup, B., Krustrup, P., Andersen, J. L., Hornstrup, T., Løwenstein, F. T., Larsen, M. A., Helge, Jørn Wulff, Póvoas, S. C. A. & Aagaard, P., 2020, In: P L o S One. 15, 11, 17 p., e0241359.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial

    Uth, J., Fristrup, B., Sørensen, V., Helge, Eva Wulff, Christensen, M. K., Kjærgaard, J. B., Møller, T. K. T., Mohr, M., Helge, Jørn Wulff, Jørgensen, Niklas Rye, Rørth, M., Vadstrup, E. S. & Krustrup, P., 2020, In: Progress in Cardiovascular Diseases. 63, 6, p. 792-799 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Exercise training results in depot-specific adaptations to adipose tissue mitochondrial function

    Mendham, A. E., Larsen, Steen, George, C., Adams, K., Hauksson, J., Olsson, T., Fortuin-de Smidt, M. C., Nankam, P. A. N., Hakim, O., Goff, L. M., Pheiffer, C. & Goedecke, J. H., 2020, In: Scientific Reports. 10, 1, 14 p., 3785.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Folate stress induces SLX1- and RAD51-dependent mitotic DNA synthesis at the fragile X locus in human cells

    Garribba, L., Bjerregaard, Victoria Alexandra, Gonçalves Dinis, M. M., Özer, Ö., Wu, Wei, Sakellariou, D., Pena-Diaz, J., Hickson, Ian David & Liu, Ying, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 28, p. 16527-16536 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Football as Medicine against type 2 diabetes and metabolic syndrome

    de Sousa, M., Brito, J., Mohr, M., Nassis, G. P., Helge, Jørn Wulff, Pettersen, S. A., Andersen, T. R. & Krustrup, P., 2020, Football as Medicine: Prescribing Football for Global Health Promotion. Krustrup, P. & Parnell, D. (eds.). Routledge, p. 25-40 (Critical Research in Football).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  25. Published

    Frailty Index Status of Canadian Home Care Clients Improves With Exercise Therapy and Declines in the Presence of Polypharmacy

    Larsen, R. T., Turcotte, L. A., Westendorp, Rudi GJ, Langberg, Henning & Hirdes, J. P., 2020, In: Journal of the American Medical Directors Association. 21, 6, p. 766-771 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Freeloading in biomedical research

    Rozing, Maarten Pieter, van Leeuwen, T. N., Reitsma, P. H., Rosendaal, F. R. & Aziz, N. A., 2020, In: Scientometrics. 122, 1, p. 47-55 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Gene–Environment Interplay Between Physical Exercise and Fitness and Depression Symptomatology

    Johnson, W., Mortensen, Erik Lykke & Kyvik, K. O., 2020, In: Behavior Genetics. 50, 5, p. 346-362 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Heterochromatin: an epigenetic point of view in aging

    Lee, J., Kim, E. W., Croteau, D. L. & Bohr, Vilhelm, 2020, In: Experimental & Molecular Medicine. 52, 9, p. 1466-1474 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    Heterotopic Ossification after an Achilles Tendon Rupture Cannot Be Prevented by Early Functional Rehabilitation: A Cohort Study

    Magnusson, Stig Peter, Agergaard, A. S., Couppé, Christian, Svensson, R. B., Warming, S., Krogsgaard, Michael R., Kjær, Michael & Eliasson, P., 2020, In: Clinical Orthopaedics and Related Research. 478, 5, p. 1101-1108 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing

    Macheret, M., Bhowmick, Rahul, Sobkowiak, K., Padayachy, L., Mailler, J., Hickson, Ian David & Halazonetis, T. D., 2020, In: Cell Research. 30, p. 997–1008

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy

    Zheng, Jin, Akbari, M., Schirmer, C., Reynaert, M. L., Loyens, A., Lefebvre, B., Buée, L., Croteau, D. L., Galas, M. C. & Bohr, Vilhelm, 2020, In: Acta Neuropathologica Communications. 8, 1, 23 p., 25.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Histology and Function of the Rectus Abdominis Muscle in Patients With Incisional Hernia

    Jensen, K. K., Oma, E., Kjær, Michael, Jørgensen, Lars Nannestad & Andersen, J. L., 2020, In: Journal of Surgical Research. 253, p. 245-251 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase

    Venegas, A. B., Natsume, T., Kanemaki, M. & Hickson, Ian David, 2020, In: Cell Reports. 31, 3, 20 p., 107533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Inducible deletion of skeletal muscle AMPKα 1 reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

    Hingst, J. R., Kjøbsted, R., Birk, J. B., Jørgensen, N. O., Larsen, M. R., Kido, K., Larsen, J. K., Kjeldsen, S. A. S., Fentz, J., Frøsig, C., Holm, S., Fritzen, A. M., Dohlmann, T. L., Larsen, S., Foretz, M., Viollet, B., Schjerling, P., Overby, P., Halling, J. F., Pilegaard, H. & 2 others, Hellsten, Ylva & Wojtaszewski, Jørgen F P, 2020, In: Molecular Metabolism. 40, 17 p., 101028.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Infant Socioeconomic Position and Quality of Life in Midlife: A 50-Year Follow-Up Study of 2079 Individuals in Denmark

    Hegelund, Emilie Rune, Folker, A. P., Wimmelmann, Cathrine Lawaetz, Just-Østergaard, E., Mortensen, Erik Lykke & Flensborg-Madsen, Trine, 2020, In: Applied Research in Quality of Life. 15, p. 937–951 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours

    Harpelunde Poulsen, K., Nielsen, J. E., Grønkær Toft, B., Joensen, Ulla Nordström, Rasmussen, Lene Juel, Blomberg Jensen, M., Mitchell, R. T., Juul, Anders, Rajpert-De Meyts, E. & Jørgensen, Anders, 2020, In: BMC Cancer. 20, 1, 14 p., 349.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Influence of the integrin alpha-1 subunit and its relationship with high-fat diet upon extracellular matrix synthesis in skeletal muscle and tendon

    Bayer, M. L., Svensson, R. B., Schjerling, P., Williams, A. S., Wasserman, D. H. & Kjær, Michael, 2020, In: Cell and Tissue Research. 381, 1, p. 177-187

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase

    Duan, S., Han, X., Akbari, M., Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6530–6546

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects

    van der Spoel, E., Roelfsema, F., Akintola, A. A., Jansen, S. W., Slagboom, P. E., Westendorp, Rudi GJ, Blauw, G. J., Pijl, H. & van Heemst, D., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 4, p. e1201–e1214 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Key Components of Human Myofibre Denervation and Neuromuscular Junction Stability are Modulated by Age and Exercise

    Søndenbroe, C., Bechshøft, C. J. L., Heisterberg, M. F., Jensen, S. M., Bomme, E., Schjerling, Peter, Karlsen, Anders, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2020, In: Cells. 9, 4, 893.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Long-term exposure to air pollution and stroke incidence: A Danish Nurse cohort study

    Amini, H., Dehlendorff, C., Lim, Y-H., Mehta, A., Jørgensen, J. T., Mortensen, L. H., Westendorp, R., Hoffmann, B., Loft, S., Cole-Hunter, T., Bräuner, E. V., Ketzel, M., Hertel, O., Brandt, J., Solvang Jensen, S., Christensen, J. H., Geels, C., Frohn, L. M., Backalarz, C., Simonsen, M. K. & 1 others, Andersen, Zorana Jovanovic, 2020, In: Environment International. 142, 8 p., 105891.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Low-Grade Inflammation Is Not Present in Former Obese Males but Adipose Tissue Macrophage Infiltration Persists

    Ara, I., Auerbach, P., Larsen, Steen, Mata, E., Stallknecht, Bente Merete, Ploug, Thorkil, Prats Gavalda, Clara & Helge, Jørn Wulff, 2020, In: Biomedicines. 8, 5, 10 p., 123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Macrophage Subpopulations and the Acute Inflammatory Response of Elderly Human Skeletal Muscle to Physiological Resistance Exercise

    Jensen, S. M., Bechshøft, C. J. L., Heisterberg, M. F., Schjerling, P., Andersen, J. L., Kjær, Michael & Mackey, Abigail, 2020, In: Frontiers in Physiology. 11, 15 p., 811.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Maintenance of muscle strength following a one-year resistance training program in older adults

    Gylling, A. T., Bloch-Ibenfeldt, M., Eriksen, C. S., Ziegler, A. K., Wimmelmann, Cathrine Lawaetz, Bækgaard, M., Boraxbekk, CJ, Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, 2020, In: Experimental Gerontology. 139, 111049.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Men Have a Stronger Monocyte-Derived Cytokine Production Response upon Stimulation with the Gram-Negative Stimulus Lipopolysaccharide than Women: A Pooled Analysis Including 15 Study Populations

    Beenakker, K. G. M., Westendorp, Rudi GJ, de Craen, A. J. M., Chen, S., Raz, Y., Ballieux, B. E. P. B., Nelissen, R. G. H. H., Later, A. F. L., Huizinga, T. W., Slagboom, P. E., Boomsma, D. I. & Maier, A. B., 2020, In: Journal of Innate Immunity. 12, p. 142-153 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test

    Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Ritz, C., Larsen, S., Dela, Flemming & Helge, Jørn Wulff, 2020, In: Journal of Applied Physiology. 128, 3, p. 681-687 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Mitochondrial Function in Gilles de la Tourette Syndrome Patients With and Without Intragenic IMMP2L Deletions

    Bjerregaard, Victoria Alexandra, Schönewolf-Greulich, B., Rasmussen, Lene Juel, Desler, Claus & Tümer, Asuman Zeynep, 2020, In: Frontiers in Neurology. 11, 9 p., 163.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Mitochondrial adaptations to high intensity interval training in older females and males

    Chrois, K. M., Dohlmann, T. L., Sogaard, D., Hansen, Camilla Collin, Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2020, In: European Journal of Sport Science. 20, 1, p. 135-145

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Mitochondrial dysfunction in adults after out-of-hospital cardiac arrest

    Wiberg, S., Stride, N., Bro-Jeppesen, J., Holmberg, M. J., Kjærgaard, J., Larsen, Steen, Donnino, M. W., Hassager, Christian & Dela, Flemming, 2020, In: European Heart Journal: Acute Cardiovascular Care. 9, 4, p. S138–S144 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Mitochondrial dysfunction induced by variation in the non-coding genome – A proposed workflow to improve diagnostics

    du Mee, D. J. M., Bak, M., Østergaard, Elsebet & Rasmussen, Lene Juel, 2020, In: Mitochondrion. 53, p. 255-259

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    MitophAging: Mitophagy in Aging and Disease

    Bakula, Daniela Janina & Scheibye-Knudsen, Morten, 2020, In: Frontiers in Cell and Developmental Biology. 8, 16 p., 239.

    Research output: Contribution to journal › Review › Research › peer-review

  52. Published

    Mitophagy and Neuroprotection

    Lou, G., Palikaras, K., Lautrup, S., Scheibye-Knudsen, Morten, Tavernarakis, N. & Fang, E. F., 2020, In: Trends in Molecular Medicine. 26, 1, p. 8-20

    Research output: Contribution to journal › Review › Research › peer-review

  53. Published

    Modification of oxygen consumption and blood flow in mouse somatosensory cortex by cell-type-specific neuronal activity

    Dahlqvist, M. K., Thomsen, Kirsten Joan, Postnov, D. D. & Lauritzen, Martin, 2020, In: Journal of Cerebral Blood Flow and Metabolism. 40, 10, p. 2010-2025 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Mortality Following Trajectories of Mobility Limitations: The Modifying Impact of Social Factors

    Jørgensen, Terese Sara Høj, Siersma, Volkert Dirk, Lund, Rikke & Nilsson, Charlotte Juul, 2020, In: Journal of Aging and Health. 32, 3-4, p. 134-142 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    New methodologies in ageing research

    Osborne, Brenna, Bakula, Daniela Janina, Ben Ezra, Michael, Dresen, C., Hartmann, E., Kristensen, S. M., Mkrtchyan, Garik, Nielsen, M. H., Petr, Michael Angelo & Scheibye-Knudsen, Morten, 2020, In: Ageing Research Reviews. 62, 11 p., 101094.

    Research output: Contribution to journal › Review › Research › peer-review

  56. Published

    No detectable remodelling in adult human menisci: an analysis based on the C14 bomb pulse

    Våben, C., Heinemeier, K. M., Schjerling, P., Olsen, J., Petersen, Michael Mørk, Kjær, Michael & Krogsgaard, Michael R., 2020, In: British Journal of Sports Medicine. 54, 23, p. 1433-1437

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Onset of Workplace Bullying and Risk of Weight Gain: A Multicohort Longitudinal Study

    Xu, Tianwei, Magnusson Hanson, L. L., Clark, A. J., Ersbøll, A. K., Westerlund, H., Madsen, I. E. H., Rugulies, Reiner Ernst, Pentti, J., Stenholm, S., Vahtera, J., Sørensen, J. K., Nordentoft, M., Westendorp, Rudi GJ, Hansen, Åse Marie, Oksanen, T., Virtanen, M., Kivimäki, M. & Rod, Naja Hulvej, 2020, In: Obesity. 28, 11, p. 2216-2223 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Perceived stress and dementia: Results from the Copenhagen city heart study

    Nabe-Nielsen, Kirsten, Rod, Naja Hulvej, Hansen, Åse Marie, Prescott, Eva, Grynderup, M. B., Islamoska, S., Ishtiak-Ahmed, K., Garde, Anne Helene, Gyntelberg, F., Mortensen, Erik Lykke, Thien Kieu Thi Phung, Waldemar, Gunhild & Westendorp, Rudi GJ, 2020, In: Aging & Mental Health. 24, 11, p. 1828-1836 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans

    Morville, T., Sahl, Ronni Eg, Moritz, Thomas, Helge, Jørn Wulff & Clemmensen, Christoffer, 2020, In: Cell Reports. 33, 13, 14 p., 108554.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Possible Modifiers of the Association Between Change in Weight Status From Child Through Adult Ages and Later Risk of Type 2 Diabetes

    Bjerregaard, L. G., Wasenius, N., Nedelec, R., Gjærde, L. K., Ängquist, Lars, Herzig, K., Jensen, G. B., Mortensen, Erik Lykke, Osler, Merete, Overvad, K., Skaaby, T., Tjønneland, Anne, Sørensen, Thorkild I.A., Järvelin, M., Eriksson, J. G., Sebert, S. & Baker, J. L., 2020, In: Diabetes Care. Supplement. 43, 5, p. 1000-1007 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Preserved capacity for satellite cell proliferation, regeneration, and hypertrophy in the skeletal muscle of healthy elderly men

    Karlsen, Anders, Soendenbroe, C., Malmgaard‐clausen, N. M., Wagener, F., Moeller, C. E., Senhaji, Z., Damberg, K., Andersen, J. L., Schjerling, P., Kjær, Michael & Mackey, Abigail, 2020, In: The FASEB Journal. 34, 5, p. 6418-6436

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Protecting the Aging Genome

    Petr, Michael Angelo, Tulika, T., Carmona Marin, Lina Maria & Scheibye-Knudsen, Morten, 2020, In: Trends in Cell Biology. 30, 2, p. 117-132 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  63. Published

    Proteomics identifies differences in fibrotic potential of extracellular vesicles from human tendon and muscle fibroblasts

    Yeung, C. C., Schoof, E. M., Tamáš, M., Mackey, Abigail & Kjær, Michael, 2020, In: Cell Communication and Signaling. 18, 1, 15 p., 177.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome

    Wu, Wei, Bhowmick, Rahul, Vogel, Ivan, Özer, Ö., Ghisays, F., Thakur, R. S., Sanchez de Leon, E., Richter, P. H., Ren, L., Petrini, J. H., Hickson, Ian David & Liu, Ying, 2020, In: Nature Structural & Molecular Biology. 27, 5, p. 424-437 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Regional collagen turnover and composition of the human patellar tendon

    Zhang, C., Couppé, Christian, Scheijen, J. L. J. M., Schalkwijk, C. G., Kjær, Michael, Magnusson, Stig Peter & Svensson, R. B., 2020, In: Journal of Applied Physiology. 128, 4, p. 884-891

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Regional differences in turnover, composition, and mechanics of the porcine flexor tendon

    Zhang, C., Svensson, R. B., Couppé, Christian, Schjerling, P., Skovgaard, D., Kjær, Michael & Magnusson, Stig Peter, 2020, In: Connective Tissue Research. 61, 5, p. 475-484

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes

    Xing, M., Zhang, F., Liao, H., Chen, S., Che, L., Wang, X., Bao, Z., Ji, F., Chen, G., Zhang, H., Li, W., Chen, Z., Liu, Ying, Hickson, Ian David, Shen, H. & Ying, S., 2020, In: Molecular Cell. 78, 4, p. 714-724.e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Reply to Dutheil et al

    Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Journal of applied physiology (Bethesda, Md. : 1985). 129, 1, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  69. Published

    Self-Disorders in Asperger Syndrome Compared to Schizotypal Disorder: A Clinical Study

    Nilsson, M., Arnfred, Sidse Marie , Lohmann, Jessica Mariana Carlsson, Nylander, L., Pedersen, L., Mortensen, Erik Lykke & Handest, P., 2020, In: Schizophrenia Bulletin. 46, 1, p. 121-129

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

    Covarrubias, A. J., Kale, A., Perrone, R., Lopez-Dominguez, J. A., Pisco, A. O., Kasler, H. G., Schmidt, M. S., Heckenbach, I., Kwok, R., Wiley, C. D., Wong, H. S., Gibbs, E., Iyer, S. S., Basisty, N., Wu, Q., Kim, I. J., Silva, E., Vitangcol, K., Shin, K. O., Lee, Y. M. & 11 others, Riley, R., Ben-Sahra, I., Ott, M., Schilling, B., Scheibye-Knudsen, Morten, Ishihara, K., Quake, S. R., Newman, J., Brenner, C., Campisi, J. & Verdin, E., 2020, In: Nature Metabolism. 2, 11, p. 1265-1283 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Serotonin transporter gene (SLC6A4) variation and sensory processing sensitivity—Comparison with other anxiety-related temperamental dimensions

    Licht, C. L., Mortensen, Erik Lykke, Hjordt, L. V., Stenbæk, Dea Siggaard, Arentzen, T. E., Nørremølle, Anne & Knudsen, Gitte Moos, 2020, In: Molecular Genetics and Genomic Medicine. 8, 8, 10 p., e1352.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Shift work and incidence of dementia: A Danish Nurse Cohort study

    Jørgensen, J. T., Hansen, J., Westendorp, Rudi GJ, Nabe-Nielsen, Kirsten, Stayner, L. T., Simonsen, M. K. & Andersen, Zorana Jovanovic, 2020, In: Alzheimer's and Dementia. 16, 9, p. 1268-1279 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Simvastatin improves mitochondrial respiration in peripheral blood cells

    Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Skeletal Effects of Levothyroxine for Subclinical Hypothyroidism in Older Adults: A TRUST Randomized Trial Nested Study

    Gonzalez Rodriguez, E., Stuber, M., Del Giovane, C., Feller, M., Collet, T. H., Löwe, A. L., Blum, M. R., van Vliet, N. A., van Heemst, D., Kearney, P. M., Gussekloo, J., Mooijaart, S., Westendorp, Rudi GJ, Stott, D. J., Aeberli, D., Bauer, D. C., Hans, D. & Rodondi, N., 2020, In: The Journal of clinical endocrinology and metabolism. 105, 1, p. 336–343 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Skærmbesøg: det sundhedsfaglige blik i en Coronatid

    Grünenberg, Kristina, Hillersdal, Line & Winther, J., 2020, In: Tidsskrift for forskning i sygdom og samfund. 17, 33, p. 189-195

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Social Relations, Community Engagement and Potentials: A Qualitative Study Exploring Resident Engagement in a Community-Based Health Promotion Intervention in a Deprived Social Housing Area

    Srivarathan, Abirami, Lund, Rikke, Christensen, Ulla & Kristiansen, Maria, 2020, In: International Journal of Environmental Research and Public Health. 17, 7, 18 p., 2341.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease

    Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Desler, Claus, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In: iScience. 23, 10, 42 p., 101556.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Steady-state visual evoked potential temporal dynamics reveal correlates of cognitive decline

    Richard, N., Nikolic, M., Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin & Benedek, K., 2020, In: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 131, 4, p. 836-846 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Supraphysiological protection from replication stress does not extend mammalian lifespan

    Albers, E., Avram, Alexandra Ioana, Sbroggio, M., Fernandez-Capetillo, O. & Lopez-Contreras, Andres, 2020, In: Aging. 12, 7, p. 5612-5624 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    TIP60 in aging and neurodegeneration

    Li, Zhiquan & Rasmussen, Lene Juel, 2020, In: Ageing Research Reviews. 64, 101195.

    Research output: Contribution to journal › Review › Research › peer-review

  81. Published

    Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing

    Gilmour, B. C., Gudmundsrud, R., Frank, J., Hov, A., Lautrup, S., Aman, Y., Rosjo, H., Brenner, C., Ziegler, M., Tysnes, O., Tzoulis, C., Omland, T., Soraas, A., Holmoy, T., Bergersen, L. H., Storm-Mathisen, J., Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 186, 6 p., 111208.

    Research output: Contribution to journal › Review › Research › peer-review

  82. Published

    The Children's Yale-Brown Obsessive-Compulsive Scale's auxiliary items: Long-term outcome

    Jensen, S., Hybel, K. A., Højgaard, D. R. M. A., Nissen, J. B., Skarphedinsson, G., Torp, N. C., Ivarsson, T., Weidle, B., Mortensen, Erik Lykke, Carlsen, A. H., Melin, K., Compton, S. & Thomsen, P. H., 2020, In: Journal of Obsessive-Compulsive and Related Disorders. 27, 100589.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    The Demand-Control model and work-related threats and violence: Short- and long-term associations

    Andersen, L. P., Biering, K., Høgh, A., Gadegaard, C. A. & Conway, Paul Maurice, 2020, In: Work. 65, 3, p. 573-580 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    The Modifying Influence of Family Social Background on the Association between IQ and Unsuccessful Educational and Occupational Achievement: A Register-Based Study of 277,938 Men in Denmark 1981-2016

    Hegelund, Emilie Rune, Flensborg-Madsen, Trine, Dammeyer, Jesper & Mortensen, Erik Lykke, 2020, In: Journal of Individual Differences. 41, 3, p. 133-143 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications

    Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells

    Brannvoll, A., Xue, X., Kwon, Y., Kompocholi, Smaragda, Simonsen, Anne Katrine Wrist, Bagge, Keerthana Stine Viswalingam, Gonzalez, L., Hickson, Ian David, Østergaard, Vibe Hallundbæk, Mankouri, H. W., Sung, P. & Lisby, Michael, 2020, In: Cell Reports. 32, 1, 25 p., 107849.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    The effect of 4 months exercise training on systemic biomarkers of cartilage and bone turnover in hip osteoarthritis patients

    Ellegaard, M., Bieler, T., Beyer, N., Kjær, Michael & Jørgensen, Niklas Rye, 2020, In: Translational Sports Medicine. 3, 1, p. 16-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    The influence of educational attainment on intelligence

    Hegelund, Emilie Rune, Grønkjær, M. S., Osler, Merete, Dammeyer, Jesper, Flensborg-Madsen, Trine & Mortensen, Erik Lykke, 2020, In: Intelligence. 78, 101419.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    The influence of prolonged strength training upon muscle and fat in healthy and chronically diseased older adults

    Gylling, A. T., Eriksen, C. S., Garde, Ellen, Wimmelmann, Cathrine Lawaetz, Reislev, N. L., Bieler, T., Ziegler, A. K., Andersen, K. W., Bauer, C., Dideriksen, K., Bækgaard, M., Mertz, K. H., Bayer, M. L., Bloch-Ibenfeldt, M., Boraxbekk, CJ, Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, 2020, In: Experimental Gerontology. 136, 110939.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    The lactate receptor HCA1 is present in the choroid plexus, the tela choroidea, and the neuroepithelial lining of the dorsal part of the third ventricle

    Hadzic, A., Nguyen, T. D., Hosoyamada, M., Tomioka, N. H., Bergersen, L. H., Storm-Mathisen, J. & Morland, C., 2020, In: International Journal of Molecular Sciences. 21, 18, 14 p., 6457.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    The many lives of type IA topoisomerases

    Bizard, A. H. & Hickson, Ian David, 2020, In: Journal of Biological Chemistry. 295, 20, p. 7138-7153 16 p.

    Research output: Contribution to journal › Review › Research › peer-review

  92. Published

    The prevention and resolution of DNA replication–transcription conflicts in eukaryotic cells

    Wu, Wei, Hickson, Ian David & Liu, Ying, 2020, In: Genome Instability & Disease. 1, 3, p. 114–128 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  93. Published

    The relationship between peak fat oxidation and prolonged double-poling endurance exercise performance

    Rømer, Tue, Hansen, Mikkel Thunestvedt, Frandsen, J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Scandinavian Journal of Medicine & Science in Sports. 30, 11, p. 2044-2056

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure

    Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Towards Inclusive Healthcare Delivery: Potentials and Challenges of Human-Centred Design in Health Innovation Processes to Increase Healthy Aging

    Sandholdt, Catharina Thiel, Cunningham, J., Westendorp, Rudi GJ & Kristiansen, Maria, 2020, In: International Journal of Environmental Research and Public Health. 17, 12, 9 p., 4551.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Trauma-affected refugees treated with basic body awareness therapy or mixed physical activity as augmentation to treatment as usual -A pragmatic randomised controlled trial

    Nordbrandt, M. S., Sonne, C., Mortensen, Erik Lykke & Carlsson, J., 2020, In: PLoS ONE. 15, 3, 16 p., e0230300.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Traumatic brain injury and risk of dementia at different levels of cognitive ability and education

    Osler, Merete, Rozing, Maarten Pieter, Eliasen, M. H., Christensen, K. & Mortensen, Erik Lykke, 2020, In: European Journal of Neurology. 27, 2, p. 399-405 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Treatment with imagery rehearsal therapy and/or mianserin in trauma-affected refugees: results from a randomized controlled trial

    Sandahl, H., Jennum, Poul, Baandrup, Lone, Mortensen, Erik Lykke & Carlsson, J., 2020, In: Journal of Sleep Research. 29, S1, p. 22-23 2 p., O41.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  99. Published

    Tumour predisposition and cancer syndromes as models to study gene–environment interactions

    Carbone, M., Arron, S. T., Beutler, B., Bononi, A., Cavenee, W., Cleaver, J. E., Croce, C. M., D’Andrea, A., Foulkes, W. D., Gaudino, G., Groden, J. L., Henske, E. P., Hickson, I. D., Hwang, P. M., Kolodner, R. D., Mak, T. W., Malkin, D., Monnat, R. J., Novelli, F., Pass, H. I. & 3 others, Petrini, J. H., Schmidt, L. S. & Yang, H., 2020, In: Nature Reviews Cancer. 20, p. 533–549

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Two genetic analyses to elucidate causality in the associations between body mass index and psychological traits

    Arumae, K., Briley, D., Colodro-Conde, L., Mortensen, Erik Lykke, Jang, K., Ando, J., Kandler, C., Sørensen, Thorkild I.A., Dagher, A., Mottus, R. & Vainik, U., 2020, In: Behavior Genetics. 50, 6, p. 441 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  101. Published

    Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome

    Drost, M., Tiersma, Y., Glubb, D., Kathe, S., van Hees, S., Calléja, F., Zonneveld, J. B. M., Boucher, K. M., Ramlal, R. P. E., Thompson, B. A., Rasmussen, Lene Juel, Greenblatt, M. S., Lee, A., Spurdle, A. B., Tavtigian, S. V. & de Wind, N., 2020, In: Genetics in Medicine. 22, p. 847–856

    Research output: Contribution to journal › Journal article › Research › peer-review

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